Progress in pleural effusion cytology.docVIP

 PAGE \* MERGEFORMAT 19 Progress in pleural effusion cytology Effusion is a common clinical symptoms. Correctly identify the nature of the fluid the diagnosis and treatment of disease prognosis significance. With the improvement of laboratory diagnostic techniques in recent years, detection of pleural effusion in cell morphology, cell chromosomes and immunocytochemistry, etc. all have a greater progress, provided a more reliable clinical basis. This paper gives a brief review. First, sediment smears St. Regis St. Regis stain stain can clearly show cytoplasmic components and nuclear chromatin structure, easy to distinguish benign and malignant cells. 1. Malignant cells typical of malignant tumor cells can be seen diagnosed with malignant pleural effusion. Wang Gang [1] reported that the Act detection rate of 38.8% of tumor cells. If the slide with the cerebrospinal fluid cells, cells were collected centrifugal precipitators, as cells in the collection of up to 80.4%, it greatly increased the sensitivity, positive predictive value of 93.5%. Li Hong [2] reported that the amount of fluid for inspection to 250ml, get fresh lower fluid centrifuge smears stained the tumor cells for the first time the detection rate of 83.3%, more than three times the detection rate of 100% submission. We passed on the pleural fluid samples (5 ~ 10ml) twice a centrifugal concentration smears St. Regis stain, first low magnification scanning the entire film, in the event of suspicious cells identified sub-cell nature of the oil lens, the detection rate of malignant cells, up to 78%, specificity 94.3% [3]. 2. Rosette of blood cells adhering to tumor cells [3] containing malignant cells in pleural effusion or pericardial effusion smears will be ≥ 3 Ge white blood cells (lymphoid, myeloid, macrophages), or red blood cell adhesion to tumor cells cytoplasm around the edges to form a wreath-like, known as tumor cell adhesion of blood cells roset