Progress of chemotherapy in colorectal cancer (Review).docVIP

 PAGE \* MERGEFORMAT 10 Progress of chemotherapy in colorectal cancer (Review) [Paper Keywords] Progress in colorectal cancer chemotherapy [Abstract] colorectal cancer is a common malignancy of the digestive system, and the incidence rates are rising year by year. The treatment of colorectal cancer surgery chemotherapy, mainly based comprehensive treatment. The past years of clinical studies have shown that Adjuvant chemotherapy after radical resection of colorectal cancer can significantly improve the quality of life and survival. Postoperative adjuvant chemotherapy FOLFOX program is still frequently used programs. CPT-11, L-OHP and Xeloda application is expected to reduce the stage, creating opportunities for surgery to improve postoperative survival. Raltitrexed, some monoclonal anti-break in colorectal cancer clinical trial is still in the application. As in recent years of multi-drug resistance in colorectal cancer research, to show us the end point of breakthrough cancer treatment, for colorectal cancer multi-drug resistance reversal agents of the development and application of the treatment of colorectal cancer will make a qualitative leap. Of colorectal cancer, including colon and rectum, is a common malignant tumors of the digestive system; location of colorectal cancer incidence followed by the rectum, sigmoid colon, cecum, descending colon, transverse colon. With the aging of the global man-days and material living standards, the prevalence of colorectal cancer and mortality in our country and the world there is a gradual upward trend, is a common one of the top ten malignant tumors [1]. Relevant data show that in China the incidence of colorectal cancer is a rising trend year by year, accounting for all the malignant tumors 4 to 6, and an average annual increase rate of 4.2% [2]. The treatment of colorectal cancer surgery are mainly based comprehensive treatment, but the 3 / 4 in the diagnosis when patients have been transferred to accept radical