Prostaglandin E1 on peripheral nerve regeneration electrophysiological study.doc

 PAGE \* MERGEFORMAT 12 Prostaglandin E1 on peripheral nerve regeneration electrophysiological study Author: Shi-Wei Zhao Cui Jianli WANG Jin-chang Li Wan Guo Zhong-Yan DENG Jun [Abstract] Objective To investigate the prostaglandin E1 (PGE1) on the regeneration of peripheral nerve injury and with vitamin B1, B6 efficacy for comparison. Methods 22 patients with 30 forearm nerve injury patients (median nerve 14, ulnar nerve 16), according to admission time, were randomly divided into two vitamin B: nerve suture after oral administration of vitamin B1, B6 of 10mg / times, day 1 times, continuous medication 3 months; PGE1 Group: nerve suture by adding 0.9% after PGE1 50μ g intravenous infusion of normal saline 500ml a day one time, continuous medication for 1 month. The mean follow-up of 7 months EMG testing, determination of neuro-motor potential, sensory potential latency and amplitude. Compared with the results of two groups, with the exception of median nerve movement potential latency and ulnar nerve sensory potential amplitude was no significant difference, the rest of the indicators of PGE1 groups were superior to vitamin B group. Conclusion of prostaglandin E1 after peripheral nerve injury to promote their recovery role. [Keywords:] prostaglandin E1 vitamin B1, B6 nerve regeneration Electromyography Electrophysiological study of prostaglandin E1 on peripheral nerve regeneration [Abstract] Objective To investigate the effect of prostaglandin E1 on peripheral nerve regeneration and compare it with that of vitaminB1, B6.Methods 22 cases of 30 acute nerve cut (14 median nerves and 16 ulnar nerves) at forearm level were studied.The nerves were repaired with inside-out vein grafts to bridge the small gap (2 ~ 3mm). The patients were then randomly divided into two groups.Group A were treated with Vit B1, B6 and group B with prostaglandin E1 postoperatively.All patients were followed up for 4 to 12 months.with an average of 7 months.To detect nerve reg