Prostaglandin E1 treatment in patients with end-stage chronic renal failure Clinical.doc

 PAGE \* MERGEFORMAT 11 Prostaglandin E1 treatment in patients with end-stage chronic renal failure Clinical Of: Ji-ren Zhang Zhong Jing-Hua Wang Yong Xiang Wu Rui-Lin Liu Yuan Shenping [Abstract] Objective To evaluate the application of prostaglandin E1 (PGE1) treatment of end-stage chronic renal failure (ESRF) of clinical efficacy. Methods 22 patients with end-stage chronic renal failure (ESRF) in elderly patients into two groups, the control group 10 cases, according to Conventional disease medication to control blood pressure, correction of anemia, acidosis, electrolyte disorders. experimental group of 12 patients without the use of group based on the use PGE1 200 g in 10% glucose solution 500 ml intravenously, 1 / d, 3 courses of treatment were followed up for 3 months were observed in the clinical symptoms, laboratory tests, mortality and other related indicators. Results The edema, backache, fatigue, urine output, loss of appetite, skin itching and other symptoms than the control group improvement obvious. experimental urea nitrogen (BUN), creatinine (Scr), endogenous creatinine clearance rate (Ccr), urinary protein control group, the difference was significant (P lt;0.05). 25% mortality in the experimental group, 50% of the control group mortality difference between two groups were significantly (P lt;0.05). Conclusions PGE1 can slow down the process of chronic renal insufficiency, improving renal function and reduce mortality in end-stage chronic renal failure and improve prognosis. [Keywords:] prostaglandin E1; end stage chronic renal failure [Abstract] ObjectiveTo investigate the effect of prostaglandin-E1 (PGE1) on the treatment for end-stage renal failure (ESRF). Methods22 patients with ESRFwere chosen and divided into groups with and without PGE1 treatment. Patientsinboth groups were given basic treatment. PGE1 was added into group with PGE1 treatment. Patients of both groups were followed up for 3 months. Blood urea nitrogen (BUN), se