Rattan tea flavonoids on human gastric cancer SGC-7901 Experimental Study of inhibition of cell proliferation.docVIP

 PAGE \* MERGEFORMAT 8 Rattan tea flavonoids on human gastric cancer SGC-7901 Experimental Study of inhibition of cell proliferation Author: Zheng writing, Guo-xian, MAO Jian, Tan for the [Abstract] Objective To investigate the vine tea flavonoids in vitro anti-tumor effect. Methods MTT method, growth curve, cell colony formation was observed vine tea flavonoids on human gastric cancer SGC-7901 cells, inhibitory effect. Results vine tea flavonoids can inhibit in vitro the growth of SGC-7901 cells, MTT method IC50 for 20.71μ g * ml-1; cell growth curve of its prompt the growth of SGC-7901 cells, there was a marked inhibition; colony-forming France, when the drug concentration in the 9.90μ g * ml-1 inhibition rate above 100%, when the drug concentration of 6.60μ g * ml-1 the inhibitory rate of 69.80%, when the drug concentration of 4.40μ g * ml-1 the inhibitory rate of of 30.23%. Conclusion vine tea flavonoids on in vitro growth of SGC-7901 cells significantly inhibited. [Keywords:] Vine anti-tumor effects of tea flavonoids SGC-7901 cell line Abstract: Objective To investigate the anti-tumor effect of Vine tea extract in vitro.MethodsThe growth inhibition was analyzed by MTT, cell colony and cell growth curve measurement in the stomach cancer cell SGC-7901.ResultsVine tea extract could obviously inhibit the growth of cultured SGC-7901 cells, the IC50 in MTT assay was 20.71 μ g * ml-1; Vine tea extract could obviously affect the tumor cell growth.The inhibitory ratio in cell colony assay was 100% when medicine density was over 9.90 μ g * ml - 1, the repressive ratio in cell colony assay was 69.80% when medicine density was 6.60 μ g * ml-1; the repressive ratio in cell colony assay was 30.23% when medicine density was 4.40 μ g * ml-1. ConclusionVine tea extract can inhibit the growth of SGC-7901 in vitro. Keywords:: Vine tea extract; Anti-tumor effect; SGC-7901; Cell line Vine Tea Ampelopsis grossedentata (Hand-Mazz) WTWang Department of Vitaceae Am