Recombinant human epidermal growth factor on clinical study of skin expansion.doc

 PAGE \* MERGEFORMAT 7 Recombinant human epidermal growth factor on clinical study of skin expansion Of: Wang Tao, Lin YA, Liu Dahai, ZHANG Rui [Abstract] Objective To observe the recombinant human epidermal growth factor (rhEGF) in the clinical application of intraoperative expansion. Methods A total of 32 patients with 78 expander embedded randomly divided into treatment and control groups, using self control, the treatment group regular expansion in the expander, while injection rHEGF, the control group, only routine expansion. measuring the expansion rate of the two groups, immediate retraction rate. expansion of the treatment group to the rated capacity of the time, instant retraction rate than the control group decreased (P lt;0 .05), the expansion rate than the control group significantly increased (P lt;0.01). Conclusion rhEGF can promote skin expansion, lower flap retraction rate, improve the quality of skin flap to improve the therapeutic effect. [Keywords:] recombinant human epidermal growth factor, skin expansion, and promote ABSTRACT Objective To study the clinical effect of rhEGF in skin expansion. Methods 32 cases with 78 expanders planted were randomly divided into 2 groups: treatment group and control group; routine expansion was applied to both groups while injection of rhEGF into the expander was added to treatment group; self-control was adopted, the expansion rate and the immediate stretch-back rate of both groups were detected. Results The time for expanding to nominal capacity in treatment group was shorter than that in control group (P lt;0.05) and its expansion rate was higher than that of control group (P lt;0.01). Conclusions rhEGF can accelerate the expansion of skin flap, reduce its stretch-back rate, increase its quality and improve the curative effect. KEYWORDS recombinant human epidermal growth factor (rhEGF) tissue expansion acceleration Skin expansion method is often used large plastic surface scar, but a long