Recombinant human growth hormone treatment of elderly patients with burns of 54 cases.docVIP
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Recombinant human growth hormone treatment of elderly patients with burns of 54 cases
PAGE \* MERGEFORMAT 7
Recombinant human growth hormone treatment of elderly patients with burns of 54 cases
Study: Song Bin Liu Jinhui Ding Fu Li Junan phase
[Keywords:] recombinant human growth hormone, burn, effect
Recombinant human growth hormone (rhGH) can inhibit the catabolism and promote protein synthesis in the body has been recognized by (1), the paper applied to the burn unit of our hospital for burn patients rhGH treatment of deep wound healing effects were observed.
1 Materials and Methods
1.1 The object of study from September 2007 to March 2009 our hospital’s large area (gt; 50% TBSA) burn patients aged 54 cases, 34 male and 20 female, mean age (65.35 + -10.37 years). Total burn area of 68.52%, the depth of burn area (deep , ) accounted for 23.36%. all patients without severe shock, and no history of diabetes and other metabolic.
1.2 The treatment will be selected rhGH treatment group were randomly divided into 27 cases, 27 cases of the control group. Two groups were age, weight, body surface area, burn area and depth differences are not significant. Two groups of patients using the same fluid resuscitation, nutritional support , anti-infection treatment. rhGH group 4 d after injury, starting 7:00 am daily subcutaneous injection of rhGH 0.2 ~ 0.4 IU / kg (JinLei race by, Changchun Kinsey medicine), drug 2 w. control group by the same method subcutaneous injection of saline, the patient informed.
Detection of targets in 1.3 before treatment, after treatment 2 w serum total protein, albumin levels, medication 5,11,18 d fasting blood sugar levels, record donor site wounds completely healed.
1.4 Data statistical methods that use x +-s, t-test between groups.
2 Results
2.1 after treatment in both groups serum total protein, albumin level is shown in table 1.
2.2 The two changes in blood glucose levels after treatment after treatment, 5,11,18 d two groups showed no significant difference in fasting plasma glucose (Pgt
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