Research Progress on Rhubarb.docVIP

 PAGE \* MERGEFORMAT 9 Research Progress on Rhubarb Author: WANG Dong-mei SHANG Li-Tong Zhai Lu Ming-tat Abstract: The Rhubarb active ingredients, pharmacological effects and clinical applications are reviewed.  Keywords:: rhubarb; pharmacological effect; clinical application; Research 0 Introduction  Rhubarb is one of China’s traditional Chinese herbal medicine in China has 39 species and 2 varieties. Chinese rhubarb or a single flavor compound rhubarb preparations for treatment of constipation, diarrhea, early, blood heat spit bleed at the nose, congestion and so on amenorrhea. ‘Without’ reads: ‘Under the blood stasis, blood closed cold and heat, breaking Zhengjia accumulation, leaving drink Sushi, and cleaned up the stomach, pushing Chen Zhixin, Tom Lee Water Valley, the technology transfer food, peaceful and five internal organs’. ‘Compendium of Materia Medica’: ‘diarrhea Chi Bai, where acute abdominal pain, urine pouring Lek, excess heat, dry knots, hot flushes and delirium, jaundice, sore various fire’. Can be seen that there are many effects of rhubarb, clinical applications are very extensive.  Active ingredient in a rhubarb  The study found the main active ingredients anthraquinone derivatives, total about 3% to 5%, to exist in two forms, some free, most of anthracene and glucose combined into glycoside. Free type of Anthraquinone Derivatives with rhein, aloe-emodin, emodin, and rhubarb phenol ether, the content less, for the anti-bacterial ingredients. Combination of derivatives of anthraquinone glucoside free class or two anthrone glycosides, the major diarrhea for the rhubarb ingredients, including pairs of anthrone glycosides diarrhea the best. Pairs of senna anthraquinone glycosides are glycosides A, B, C, D. In addition, still contains tannin, about 5%, for the role of the active ingredients of rhubarb convergence.  2 Rhubarb pharmacological effects and clinical application  2.1 of the digestive system  (1) the