Response Surface Optimization Mosla the extraction process of total flavonoids.doc

 PAGE \* MERGEFORMAT 11 Response Surface Optimization Mosla the extraction process of total flavonoids Of: Yan Yunliang Lvpei Hui Chen Huan Yu [Abstract] Objective: To determine the total flavonoids Mosla the best extraction conditions. Methods: The ethanol extraction method Mosla total flavonoids, determined by spectrophotometry of total flavonoids, the extraction yield of total flavonoids indicators for the study to investigate solvent ratio, extraction time and extraction times on the extraction of total flavonoids Mosla rate of use of Response Surface Optimization of extraction process, to determine the optimal extraction process of total flavonoids. Results: Fish The best of immortality flavonoids extraction technology: the amount of added ingredients 20 times the concentration of 70% ethanol, reflux extraction water bath at 90 ℃ 3 times, each time 1.9 h. Mosla under this process the extraction rate of total flavonoids 8.50%. Conclusion: The process the extraction rate and easy operation, easy for industrial mass production. [Keywords:] Mosla; flavonoids; response surface analysis Labiatae Mosla Mosla annual herb Mosla dianthera the whole plant, flower thinning chestnut limonene alias, wild Elsholtzia and so on. With Qufeng published, the effect of dampness itching, attending a cold, fever, tonsillitis , heat stroke, headache, ulcer disease [1]. For Mosla reported more volatile oil, its volatile oil containing mainly Hong Nepeta phenol, thymol, caryophyllene alcohol and other aromatic ingredients, with a good antibacterial [2]; while Mosla non-volatile parts of the study reported less. Modern research shows that the major parts of its non-volatile containing flavonoids, phenolic acids and other ingredients, antibacterial, antioxidant, anti-allergic and so on [ 3,4]. Currently on the extraction process Mosla optimization studies rarely reported. Only Liu Xiaofen et al [5] Mosla extraction process of total flavonoids were single factor, the lac