Rhinitis granules preparation and quality standards.docVIP

 PAGE \* MERGEFORMAT 15 Rhinitis granules preparation and quality standards 【Abstract】 Objective: To establish quality control standards rhinitis granules. Methods: The thin-layer chromatography for qualitative identification, using HPLC method for determination of baicalin. Results: The TLC conditions are right, spots were clear, HPLC separation of quantitative methods is good, the linear range of 10 ~ 50mg * L-1 (r = 0.9998), average recovery was 99.13%, RSD = 1.12%. Conclusion: The method is simple, rapid, accurate, and can be used as granules rhinitis quality control methods. Keywords: rhinitis granule; baicalin; HPLC Rhinitis, nasal inflammation is a common disease, with duration of lingering, recurrent features, seriously affect the patient’s work and life. Rhinitis granules in clinical use for nearly 15 years, the treatment of chronic rhinitis, nasal inflammation has a unique effect. A prescription and preparation of This product is from the skullcap, honeysuckle, licorice, Scrophulariaceae, Magnolia, Angelica, mint, loofah, etc. composed of eight Chinese herbal medicines. 1.1 Volatile oil extraction Obtained on prescription, said the proportion of Magnolia, Angelica, honeysuckle, mint, home to non-vacuum concentration tank extract oil droplets, the vacuum re-distillation initial boiling liquid, add sodium chloride to saturation, place overnight, extracted with ether reservoir, recycling ether, too volatile oil. 1.2 Preparation of dense extract According to the proportion of prescriptions that take skullcap, licorice, Scrophulariaceae, loofah and extraction of volatile oil remaining dregs mixed with 10 times the amount of water boiling 2h, filtered, then eight times the amount of residues of water boiling 1.5h, filter, merge filtrate, place overnight, concentrated to the proportion of 1.23, by adding ethanol to contain 70% alcohol, and alcohol precipitation 24h, filtration, reco