Schisandra water extract of D-galactose induced aging of the protective effect of nerve cells_0.docVIP

 PAGE \* MERGEFORMAT 8 Schisandra water extract of D-galactose induced aging of the protective effect of nerve cells Study: High Wen-rong, JIN Xiang-zi, Li Xiangdan [Abstract] Objective Schisandra water extract of D-galactose induced aging of nerve cells in rats. Methods Primary cultured neonatal rat brain cells in culture after 7 d, divided into normal control group, model group (D-gal group); the experimental group (8 g / L D-gal +750 μg / ml water extract of Schisandra, 8 g / L D-gal + 500 μg / ml water extract of Schisandra, 8 g / L D-gal + 250 μg / ml water extract of Schisandra); drug control group (8 g / L D-gal + 500 μg / ml ginsenosides), the role of 24 h, electron microscopy ultrastructural changes of cells in each group , staining cells were observed within the Nissl bodies and lipofuscin (LPF), succinate dehydrogenase (SDH), acid phosphatase (ACP) activity. Results Schisandra Extract to restore D-half lactose-induced brain injury in neonatal rat cultured nerve ultrastructure, reduced inhibition of Nissl bodies and the LPF of the deposition, increased SDH activity in nerve cells and reduce the ACP activity. Conclusion Schisandra water extract of D-galactose induced aging Protective effects of nerve cells. [Keywords:] Schisandra; D-galactose; nerve cells Schisandra Schisandra is Magnoliaceae Schisandra chinensis (TurcZ) Bail dry ripe fruit, the fruit used as medicine, taste, temperature and acidity, lung, kidney, there is convergence of the lung, ney, antiperspirants, Sheng Jin, diarrhea, astringent refined the effect of [1]. neurasthenia commonly used in clinical medicine and other evidence, has excited the central nervous system, spinal cord excitability, increased regulation of the cerebral cortex [2 ~ 4], investigated the effects of the water extract of Schisandra brain cells anti-aging role for the further development and application of Schisandra provide experimental and theoretical basis. 1 Materials and equipment 1.1 SD anima