Schisandra of different qualitative determination of water-soluble polysaccharide and its application.docVIP
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Schisandra of different qualitative determination of water-soluble polysaccharide and its application
[Abstract] The water-soluble alcohol precipitation received Schisandra polysaccharide, applied 40% ethanol precipitation was separated into A, B two parts, the determination of their molecular weight, dissolution rate and precipitation points, experimental results show that: B polysaccharide region focus not only on polysaccharide active ingredient, and good water solubility and high stability, for the preparation of polysaccharide injection to provide theoretical basis and method of operation.
[Keywords:] Schisandra; polysaccharide; nature; determination
Schisandra polysaccharides have a high medicinal value, but different delivery methods of their large differences in drug efficacy, pharmacology and experimental evidence: the efficacy of polysaccharide injection administration is the oral efficacy of 100 ~ 150 times. Injecting drug use, but very demanding. Natural polysaccharides are highly decentralized, the ideal preparation of injections more difficult. However, water-soluble polysaccharide Schisandra concentrated in two intervals, 40% of ethanol can be used refined Schisandra water-soluble polysaccharide was separated into two parts, its precipitation within the polysaccharide polysaccharide A and solution B, concentration ratio of about 65:35 . Pharmacological experiments show that only the B polysaccharide region only has a medicinal value. By measuring the molecular weight polysaccharides, dissolution rate and precipitation point, reflecting the B, polysaccharides in the water solubility and stability is much higher than the original polysaccharide and polysaccharide A zone. This Schisandra polysaccharide preparation for injection to provide a reliable theoretical basis and method of operation. Experiments are as follows.
1 Experimental apparatus and materials
1.1 Beckman Instruments SWCII temperature meter; 722 spe
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