Skin thermal pain perception and relevance of noxious stimulation.docVIP

 PAGE \* MERGEFORMAT 22 Skin thermal pain perception and relevance of noxious stimulation [Abstract] Objective To build an ability to quantify the overall skin thermal pain model. Methods thermal coupling by considering the behavior of the skin and the current pain intensity, neurological understanding of the development of a quantitative mathematical model of the overall thermal pain. Results model consists of three interconnected parts: Part modulation of noxious stimulation of nerve endings, nerve impulses will come from damage by thermal stimulation of energy into electrical energy, transmission part, these nerve signals from the transmission shift position within the skin to the spinal cord and brain, the spinal cord and brain were modulation and perception part. model predictions with experimental data reported in the literature agree well prove the feasibility and correctness of the model. Conclusion Using this model, you can create thermal nociceptive pain level and characteristics of the quantitative relationship. [Keywords:] skin, heat pain, overall model, thermal coupling model ABSTRACT: Objective The aim of this paper is to develop a holistic mathematical model to quantify the correlation between skin thermal sensation and noxious stimuli, since skin thermal pain is one of the most common problems in everyday life and the understanding of the underlying physical mechanisms is still not clear. Methods The model is developed by considering the biothermomechanical behaviour of skin tissue and by incorporating the current understanding of biophysical and neurophysiological mechanisms of pain sensation. Results The proposed model consisted of three interconnected sub-models: peripheral modulation of noxious stimuli, which converts the energy from a noxious thermal stimulus into electrical energy via nerve impulses; transmission, which transports these neural signals from the site of transduction in the skin to the spinal cord and brain; and modu