Tumor immunity status of the editing and research.docVIP

 PAGE \* MERGEFORMAT 23 Tumor immunity status of the editing and research Abstract immune system to inhibit tumor growth and malignancy degree, while the progressive strengthening of this process is referred to as “tumor immune editing.” This concept is the understanding of tumor immunology based on the constant depth, and sub-immune Clear, immunization against, three stages of immune escape. is now on the tumor immune editing process and the latest progress of the three to do a review to help design more reasonable proposal, and better anti-cancer. Keywords: immune editing; immune clearance; immune confrontation; immune escape 0 Introduction Cancer is the modern society, the common causes of death among humans. WHO report on global cancer deaths in 2000 more than 6 million cases, accounting for 12% of the number of global deaths, 21% in developed countries, in developing countries up to 9% in China, up to 1% [1].-tumor immune editor refers to the anti-tumor immune system, while gradually increasing the degree of malignant tumors, resulting in the immune system and cancer of the balance of power imbalance in the body could eventually lead to the death process. With modern science and technology, such as gene technology, transgenic technology, the development of monoclonal antibody technology, as well as the establishment of animal model of immune deficiency, scholars from various angles confirmed the correctness of the idea. In addition, experimental study also showed that the immune the system of anti-tumor tissue and also to promote the development of a malignant tumor. the immune system can recognize and kill tumor tissue, can promote the malignant tumor of the extent of increase, this dual role was recognized, the tumor immunity doctrine before editing formally been proposed [2-3]. Through years of experiments and clinical observation, the University of Washington Cancer Center raised further editing 3-tumor immune process, in which