Xuebijing injection on patients with severe acute pancreatitis TNF-α IL-10 of.docVIP

 PAGE \* MERGEFORMAT 23 Xuebijing injection on patients with severe acute pancreatitis TNF-α IL-10 of Author: ZHANG Xiaofeng Xu Ping Zhao Guohai 【Abstract】 Objective To observe the blood must be a net injection on severe acute pancreatitis (SAP), serum tumor necrosis factor-α (TNF-α), interleukin -10 (IL-10) the impact of its therapeutic effect on SAP, mechanism. Methods 45 patients with SAP were randomly divided into treatment group and control group, treatment group on the basis of TCM and Western medicine treatment of blood will increase the net injection, the control group using only comprehensive treatment of Western medicine. Test before treatment and after treatment 1,3,6,10 d groups of serum TNF-α, IL-10 levels, and to evaluate the efficiency of treatment of the two groups, WBC, serum amylase recovery time, relieve abdominal pain, time, average length of stay . Results After treatment, patients treated white blood cells, serum amylase returned to normal time, abdominal pain, ease the time and the average length of stay was significantly shorter than those in the control group (P lt;0.01). Before treatment and after treatment 1d, two groups of patients with TNF-α, IL-10 levels were no statistically significant difference (Pgt; 0.05), but after treatment 3,6,10 d, the treatment group serum levels of TNF-α compared with control patients decreased significantly (P lt;0.01), while IL-10 levels than the control group patients were significantly higher (P lt;0.01). Conclusion Xuebijing injection can inhibit TNF-α secretion, increase the level of IL-1O, the SAP has a good therapeutic effect. Keywords: severe acute pancreatitis serum tumor necrosis factor-α Interleukin -10 Xuebijing Injection 【Abstract】 Objective To investigate the effects of Xuebijin injection levels on serum TNF-αand IL-10 in patients with severe acute pancreatitis (SAP) and the mechanisms. Methods 45 patients with SAP were randomly divided into 2 groups. Treating gro