Current trends in the management of extra-abdominal desmoid tumours.docVIP

World Journal of Surgical Oncology BioMedCentral Review Open Access Current trends in the management of extra-abdominal desmoid tumours Panayiotis J Papagelopoulos*1, Andreas F Mavrogenis1, Evanthia A Mitsiokapa2, Kleo Th Papaparaskeva3, Evanthia C Galanis4 and Panayotis N Soucacos1 Address: 1First Department of Orthopaedic Surgery, Athens University Medical School, Athens, Greece, 2Department of Physical Medicine and Rehabilitation, Thriassion Hospital, Elefsis, Greece, 3Department of Pathology, Hygeia Athens Medical Center, Athens, Greece and 4Department of Medical Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota Email: Panayiotis J Papagelopoulos* - pjp@hol.gr; Andreas F Mavrogenis - andreasfmavrogenis@yahoo.gr; Evanthia A Mitsiokapa - andreasfmavrogenis@yahoo.gr; Kleo Th Papaparaskeva - kleopap@; Evanthia C Galanis - galanis.evanthia@; Panayotis N Soucacos - soukakos@panafonet.gr * Corresponding author Published: 03 April 2006 Received: 14 September 2005 Accepted: 03 April 2006 World Journal of Surgical Oncology2006, 4:21 doi:10.1186/1477-7819-4-21 This article is available from: /content/4/1/21 ? 2006Papagelopoulos et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Extra-abdominal desmoid tumours are slow-growing, histologically benign tumours of fibroblastic origin with variable biologic behaviour. They are locally aggressive and invasive to surrounding anatomic structures. Magnetic resonance imaging is the modality of choice for the diagnosis and the evaluation of the tumours. Current management of desmoids involves a multidisciplinary approach. Wide margin surgical resection remains the main treatment modality for local control of the tumour. Amputation should not