Thermostability in endoglucanases is fold-specific 英文论文文献.docVIP

Yennamallietal.BMCStructuralBiology2011,11:10 /1472-6807/11/10 RESEARCH ARTICLE OpenAccess Thermostabilityinendoglucanasesisfold-specific RagothamanMYennamalli1,AndrewJRader2,JeffreyDWolt3,TanerZSen1,4,5* Abstract Background:Endoglucanasesareusuallyconsideredtobesynergisticallyinvolvedintheinitialstagesofcellulose breakdown-anessentialstepinthebioprocessingoflignocellulosicplantmaterialsintobioethanol.Despitetheir economicimportance,wecurrentlylackabasicunderstandingofhowsomeendoglucanasescansustaintheir abilitytofunctionatelevatedtemperaturesrequiredforbioprocessing,whileotherscannot.Inthi