Toll-like receptor 9 polymorphisms are associated with severity variables in a cohort of meningococcal meningitis survivors 英文论文文献.docVIP
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Toll-like receptor 9 polymorphisms are associated with severity variables in a cohort of meningococcal meningitis survivors 英文论文文献
Sandersetal.BMCInfectiousDiseases2012,12:112
/1471-2334/12/112
RESEARCH ARTICLE
OpenAccess
Toll-likereceptor9polymorphismsareassociated
withseverityvariablesinacohortof
meningococcalmeningitissurvivors
MariekeSSanders1,3,4?,GijsTJvanWell3,5?,SanderOuburg1,ServaasAMorré1,2*andAMarcelinevanFurth3
Abstract
Background:Geneticvariationinimmuneresponsegenesisassociatedwithsusceptibilityandseverityof
infectiousdiseases.Toll-likereceptor(TLR)9polymorphismsareassociatedwithsusceptibilitytodevelop
meningococcalmeningitis(MM).TheaimofthisstudyistocomparegenotypedistributionsoftwoTLR9
polymorphismsbetw
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