Topological analysis of protein co-abundance networks identifies novel host targets important for HCV infection and pathogenesis 英文论文文献.docVIP

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2017-05-08 发布于上海
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Topological analysis of protein co-abundance networks identifies novel host targets important for HCV infection and pathogenesis 英文论文文献.doc

Topological analysis of protein co-abundance networks identifies novel host targets important for HCV infection and pathogenesis 英文论文文献

McDermottetal.BMCSystemsBiology2012,6:28 /1752-0509/6/28 RESEARCH ARTICLE OpenAccess Topologicalanalysisofproteinco-abundance networksidentifiesnovelhosttargetsimportant forHCVinfectionandpathogenesis JasonEMcDermott1,DeborahLDiamond2,CourtneyCorley3,AngelaLRasmussen2,MichaelGKatze2and KatrinaMWaters1* Abstract Background:High-throughputmethodsforobtainingglobalmeasurementsoftranscriptandproteinlevelsin biologicalsampleshasprovidedalargeamountofdataforidentificationof‘target’genesandproteinsofinterest. Thesetargetsmaybemediatorsoffunctionalprocessesinvolvedindiseaseandthereforerepresentkeypoi

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Topological analysis of protein co-abundance networks identifies novel host targets important for HCV infection and pathogenesis 英文论文文献.docVIP