原创力文档Transcriptomic analysis of dystrophin RNAi knockdown reveals a central role for dystrophin in muscle differentiation and contractile apparatus organization 英文论文文献.docVIP
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Transcriptomic analysis of dystrophin RNAi knockdown reveals a central role for dystrophin in muscle differentiation and contractile apparatus organization 英文论文文献
GhahramaniSenoetal.BMCGenomics2010,11:345
/1471-2164/11/345
RESEARCH ARTICLE
OpenAccess
TranscriptomicanalysisofdystrophinRNAi
knockdownrevealsacentralrolefordystrophin
inmuscledifferentiationandcontractile
apparatusorganization
MohammadMGhahramaniSeno1,2?,CapucineTrollet1?,TakisAthanasopoulos1,IanRGraham1,3,PingzhaoHu2,
GeorgeDickson1*
Abstract
Background:Duchennemusculardystrophy(DMD)isafatalmusclewastingdisordercausedbymutationsinthe
dystrophingene.DMDhasacomplexandasyetincompletelydefinedmolecularpathophysiologyhindering
developmentofeffectiveameliorativeapproaches.Transcriptomicstudies
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