Ubiquitin ligases and beyond 英文论文文献.docVIP

Dikic and Robertson BMC Biology 2012, 10:22 /1741-7007/10/22 EDITORIAL Open Access Ubiquitin ligases and beyond Ivan Dikic and Miranda Robertson 1,* 2,* In a review published in 2004 [1] and that still repays reading today, Cecile Pickart traced the evolution of research on ubiquitination from its origins in the proteasomal degradation of proteins through the revelation that it has a central role in cell cycle regulation Where are we now? Ubiquitin is a protein of 76 a