天然产物抗氧化活性成分研究进展_王忠雷.pdfVIP

- 386 - Drug Evaluation Research 第 35 卷 第 5 期 2012 年 10 月 天然产物抗氧化活性成分研究进展 1 2 1* 3 1 1 王忠雷 ，杨丽燕 ，张小华 ，曾祥伟 ，李朋收 ，潘激扬 1. 北京中医药大学 中药学院，北京 100102 2. 中国石油大学 理学院，北京 102249 3. 北京丰泰金源药业有限公司，北京 102212 摘 要：天然产物抗氧化剂在自然界有广泛的分布，研究表明多糖、黄酮、多酚、生物碱、皂苷、维生素等天然产物均能有 效清除自由基以保护机体健康。随着人们回归自然思潮的兴起及安全意识的提高，天然抗氧化剂因其高效、低毒更是倍受关 注。从天然产物中寻找新的清除体内自由基的抗氧化剂已成为现代医药、保健行业发展的必然趋势。综述了天然产物抗氧化 活性成分的研究进展，以期为天然产物抗氧化活性的研究和发展提供参考。 关键词：天然产物；抗氧化活性；自由基 中图分类号：R977.9 文献标志码：A 文章编号：1674 - 6376 (2012) 05 - 0386 - 04 Research progress on active anti-oxidative components from natural products 1 2 1 3 1 1 WANG Zhong-lei , YANG Li-yan , ZHANG Xiao-hua , ZENG Xiang-wei , LI Peng-shou , PAN Ji-yang 1. School of Chinese Materia Medica, Beiing University of Chinese Medicine, Beijing 100102, China 2. College of Science, China University of Petroleum, Beijing 102249, China 3. Beijing Fengtai Jinyuan Pharmaceutical Co., Ltd., Beijing 102212, China Abstract: The natural anti-oxidant has an extensive distribution in the nature. Research have shown that natural products such as polysaccharide, flavonoid, polyphenol, alkaloid, saponin, vitamin, and so on could safely and effectively scavenge free radicals and protect body health. With the trend of the return to nature and the enhancement of safety consciousness, people pay more attention to the natural anti-oxidant because of its high efficiency and low poison. It has become an inevitable trend for the modern medicine and the health care industries to find new anti-oxidant from natural products. Now it summarized research progress of the activated components coming from natural products, which played the anti-oxidative function, so as to provide some references for the research and development of the natural anti-