异维A酸组和维胺酯组治疗痤疮的比较.pdfVIP

比较治疗学 医学与哲学{临床决策论坛版)2009 年 6 月第 30 卷第 6 期总第 383 期 异维 A 酸组和维肢E旨组治疗痒疮的比较 田黎明① 谢红付①· 贺达仁② 姚明珠① 刘雷山① 摘要:为了比较分析异维 A 酸纽和维接酶纽治疗瘟疮的临床疗效、费用和不良反应，于.nl药前后观察疗效、不良反应和相 关费用。结采显示，异维 A fë.J.且治疗瘟疮起效快。在治疗中度瘟疮，两组总体疗效、医疗费用相当，但维且是酶纽不良反应 较轻。而在治疗重度瘟疮方面，异维 A 酸纽临床疗效较维殷商纽高，且医疗成本较低。 关键词:瘟疮，异维 A 酸，维接爵.比较治疗，决策树 中国分类号:R758.733 文献标识码:A 文章编号: 1002-0772(2009 )6-0055-03 Comparison of Isotretinoin Group and Viaminate Group in the Treatment of Acoe TIAN Li-ming ,X IE Hong-fu ,H E Da- ren ,et al. Deþartment of Dermatology , Xiangya Hosþital ,Central South University , Changsha 410008 ,China Abstract:Through comparing and analyzing isotretinoin group and viaminate group in the treatment of acne from the ex- pense ,therapeutic effect ,side effect and some other aspects. All subjects were evaluated before treatment and after the ini- tiation of treatment ,for evaluation of lesion count ,and for observation of therapeutic effects and side effect and expense. Thus it can be seen , for the treatment of moderate acne ,the efficacy and the mean drug cost of isotretinoin is similar to that of viaminate; however ,isotretinoin has more immediate effect with more side effects than viaminate. For the treatment of se- vere acne ,the efficacy of isotretinoin is obviously than that of viaminate ,and the mean drug cost of isotretinoin is much low- er than that of viaminate. Key Words: acne , isotretinoin , viaminate , comparison therapy ,decision tree 瘦疮是一种毛囊、皮脂腺慢性炎症性皮肤病，其发病与多种 常者沃的职业性瘟疮或药物性瘦疮样皮掺或其他面部皮肤病 者， (5)病程少于半年者，(的人选前 2 个月口服过维甲酸类或激 因素有关，毛囊皮脂腺导管的角化异常，雄激素及皮脂腺功能亢 进，瘁疮丙酸杆菌的作用，宿主的免疫反应以及遗传等因素均参