Antarctic Genomics英文文献资料.docVIP

ComparativeandFunctionalGenomics CompFunctGenom2004;5 :230–238. PublishedonlineinWileyInterScience().DOI:10.1002/cfg.398 Feature Antarcticgenomics MelodyS.Clark1*,AndrewClarke1,CharlesS.Cockell1,PeterConvey1,H.WilliamDetrichIII2, KeironP.P.Fraser1,IanA.Johnston3,BarbaraA.Methe4,AlisonE.Murray5,LloydS.Peck1, KarinRo¨misch6andAlexD.Rogers1 1BritishAntarctic Survey,NationalEnvironment Research Council,HighCross,Madingley Road,Cambridge CB30ET,UK 2Department ofBiology,Northeastern University, Boston,MA02115,USA 3GattyMarineLaboratory, University ofStAndrews, StAndrews, FifeKY168LB,Scotland,UK 4TIGR,9712MedicalCenterDrive,Rockville, MD20850,USA 5DesertResearch Institute,2215RaggioParkway, Reno,NV89512,USA 6UniversityofCambridge, CIMRandDepartment ofClinicalBiochemistry, WellcomeTrust/MRC Building,HillsRoad,Cambridge CB22XY,UK *Correspondence to: Abstract MelodyS.Clark,BritishAntarctic Survey,HighCross,Madingley Road,Cambridge CB30ET,UK. E-mail:mscl@bas.ac.uk With the development of genomic science and its battery of technologies, polar biology stands onthethreshold ofarevolution, one thatwillenable theinvestigation of important questions of unprecedented scope and with extraordinary depth and precision. Theexotic organisms ofpolar ecosystems areidealcandidates forgenomic analysis. Through such analyses, it will be possible to learn not only the novel features that enable polar organisms to survive, and indeed thrive, in their extreme environments, but also fundamental biological principles that are common to most, if not all, organisms. This article aims to review recent developments in Antarctic genomics and to demonstrate the global context of such studies. Copyright ? 2004 John Wiley Sons, Ltd. Received:23January2004 Revised:5February2004 Accepted:11February2004 Keywords: Antarctic; genomics; psychrophilic; stenothermal; marine; terrestrial; environment; evolution Unplanned natural experiments create ecological commu- nities that we would never have drea