Antenatal and postnatal management of congenital cystic adenomatoid lung malformation diagnosed by ultrasound and Magnetic Resonance Imaging (MRI)英文文献资料.docVIP

Open Journal of Obstetrics and Gynecology, 2012, 2, 367-372 OJOG /10.4236/ojog.2012.24076 Published Online November 2012 (http://www.SciRP.org/journal/ojog/) Antenatal and postnatal management of congenital cystic adenomatoid lung malformation diagnosed by ultrasound and Magnetic Resonance Imaging (MRI) Susanne E. Gruessner , Hermann Hertel , Eva Bültmann , Charles O. A. Omwandho , 1,2* 1 3 4 6 Gerhard Alzen 5 , Corinna Peter 1 2 3 4 5 6 Department of Obstetrics, Gynaecology and Reproductive Medicine, Hannover Medical School, Hannover, Germany Department of Obstetrics and Gynaecology, Justus-Liebig-University of Giessen, Giessen, Germany Institute of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Germany Department of Biochemistry, University of Nairobi, Nairobi, Kenya Department of Pediatric Radiology, University of Giessen, Giessen, Germany Department of Pediatric Pulmonology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany Email: * gruessner.susanne@mh-hannover.de, * susanne.gruessner@gmx.de Received 4 September 2012; revised 3 October 2012; accepted 10 October 2012 ABSTRACT 1. INTRODUCTION Purpose: Antenatal diagnosis of congenital cystic ade- nomatoid lung malformation (CCAM) is vital for disease surveillance and postnatal care. Ultrasono- graphy (US) has been the imaging gold standard for antenatal CCAM assessment. However, one of the limitations of US is the “vanishing phenomenon” caused by isoechogenicity of CCAM tissue and adja- cent normal lung parenchyma. Methods: Antenatal serial US were concurrently used with magnetic re- sonance imaging (MRI) to monitor macro- and mi- crocystic lesions. Results: In both pregnant women, antenatal US and MRI confirmed the presence, in the fetus, of