Bevacizumab for Macular Serous Neuroretinal Detachment in Tilted Disk Syndrome英文文献资料.docVIP

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Bevacizumab for Macular Serous Neuroretinal Detachment in Tilted Disk Syndrome英文文献资料.doc

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Bevacizumab for Macular Serous Neuroretinal Detachment in Tilted Disk Syndrome英文文献资料

HindawiPublishingCorporation JournalofOphthalmology Volume2010,ArticleID970580,3pages doi:10.1155/2010/970580 CaseReport BevacizumabforMacularSerousNeuroretinalDetachmentin TiltedDiskSyndrome PaoloMilani, PaoloRadice, 1 AlfredoPece, LuisaPierro, PatrizioSeidenari, 2 3 1 andAntonioScialdone 1 1 1 2 3 OspedaleFatebenefratelli-Oftalmico,CorsodiPortaNuova23,Milan,Italy OspedaleVizzoloPredabissi,ViaPandina1,Melegnano,Milano,Italy OspedaleSanRa?aele,Universit`aViteeSalute,ViaOlgettina60,Milano,Italy CorrespondenceshouldbeaddressedtoPaoloMilani,dottpaolomilani@ Received29March2010;Accepted25October2010 AcademicEditor:EricEggenberger Copyright?2010PaoloMilanietal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense, whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited. Background.Tilteddiscsyndrome(TDS)isacongenitalanomalycharacterizedby“tilting”oftheopticdisctipycallyassociatedwith myopicastigmatism,visual?elddefect,inferiorstaphyloma,andretinalpigmentepitheliumatrophy.Associatedcomplications suchasmacularserousneuroretinaldetachmentarewelldescribed;however,idealtherapyforsuchcomplicationisunknown. Methods. One interventional case report is hereby described. A patient a?ected by macular serous neuroretinal detachment- complicatedtilteddisksyndromeunderwentacompleteophthalmicexamination.Opticalcoherencetomographyand?uorescein angiographyweretakenatbaselineandatscheduledvisits.Twointravitrealtreatmentsofbevacizumab(avastin,1.25mg/0.05mL) wereperformedatmonthlyinterval.Results.Atscheduledvisit,onemonthafterthesecondinjection,OCTdepictedpersistence ofneuroretinaldetachment.Best-correctedvisualacuityremainstableaswellasmetamorphopsiaandfunctionaldiscomfort. Conclusion.Clinicalevidenceofthisbriefinterventionalcasereportindicatesthatonepatienta?ectedbyrecentserousmacular detachment-complicatedTDSdidnotbene?tfrom2consecutivemonthlyintravitrealAvastintreatments.Best-correc