Certainty of patient survival with reference to game information dynamic model英文文献资料.docVIP

Vol.2, No.4, 490-498 (2012) Open Journal of Preventive Medicine /10.4236/ojpm.2012.24068 Certainty of patient survival with reference to game information dynamic model Hiroyuki Iida, Takeo Nakagawa , Nathan Nossal * 1 * School of Information Science, Japan Advanced Institute of Science and Technology, Nomi, Japan; Corresponding Author: takeo-n@jaist.ac.jp Received 18 July 2012; revised 10 September 2012; accepted 6 October 2012 ABSTRACT where the age-adjusted death rate from HCC is approxi- mately 23 per 100,000 per year. Surgical resection, liver transplantation, and radiofrequency ablation are consid- ered to be potentially curative treatments for HCC. How- ever, only a minority of patients is eligible for surgery or transplantation at the time of diagnosis, and the rate of eventual relapse with all of these therapies is high. The other treatments, including percutaneous ethanol inject- tion therapy, transarterial chemoembolization, chemo- therapy, and most recently, therapy with kinase inhibitors, are not curative but can prolong survival. Non the less, for patients with advanced liver disease and inoperable tumors, the prognosis for long-term survival with HCC is quite poor. The use of naturally occuring botanical and microbial products, one of the principals of naturopathic medicine, is another category of treatment to be considered in pa- tients with end stage malignancy for which is there is no curative treatment. This paper is concerned with Retro- spective analysis of case series of Hepato-Cellular Car- cinoma (HCC) patients treated naturopathic agents [1]. It is found that there is a significant correlation between number of agents administered and survival (p 0.0001). Patients treated with ≥4 agents survived significantly longer than patients treated with ≤3 agents (40.2 months vs. 6.4 months, p 0.00001). This difference could not be attributed to statistically significant differ