Aerobic Exercise Training Reduces Cannabis Craving and Use in Non-Treatment Seeking Cannabis-Dependent Adults 英文参考文献.docVIP

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Aerobic Exercise Training Reduces Cannabis Craving and Use in Non-Treatment Seeking Cannabis-Dependent Adults 英文参考文献.doc

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Aerobic Exercise Training Reduces Cannabis Craving and Use in Non-Treatment Seeking Cannabis-Dependent Adults 英文参考文献

AerobicExerciseTrainingReducesCannabisCravingand UseinNon-TreatmentSeekingCannabis-Dependent Adults MaciejS.Buchowski1*,NatalieN.Meade1,EvonneCharboneau2,SoheePark3,MaryS.Dietrich2,4, RonaldL.Cowan2,3,5,6,PeterR.Martin2 1EnergyBalanceLaboratory,DivisionofGastroenterology,HepatologyandNutrition,DepartmentofMedicine,VanderbiltUniversity,Nashville,Tennessee,UnitedStates ofAmerica,2AddictionCenterandPsychiatricNeuroimagingProgram,DepartmentofPsychiatry,VanderbiltUniversity,Nashville,Tennessee,UnitedStatesofAmerica, 3Department of Psychology, Vanderbilt University, Nashville, Tennessee, United States of America, 4Department of Biostatistics, School of Medicine, Vanderbilt University,Nashville,Tennessee,UnitedStatesofAmerica,5DepartmentofRadiologyandRadiologicalSciences,VanderbiltUniversity,Nashville,Tennessee,UnitedStates ofAmerica,6VanderbiltUniversityInstituteofImagingSciences,VanderbiltUniversity,Nashville,Tennessee,UnitedStatesofAmerica Abstract Background:Cannabisdependenceisasignificantpublichealthproblem.Becausetherearenoapprovedmedicationsfor this condition, treatment must rely on behavioral approaches empirically complemented by such lifestyle change as exercise. Aims:Toexaminetheeffectsofmoderateaerobicexerciseoncannabiscravinganduseincannabisdependentadultsunder normallivingconditions. Design: Participants attended 10 supervised 30-min treadmill exercise sessions standardized using heart rate (HR) monitoring(60–70%HRreserve)over2weeks.Exercisesessionswereconductedbyexercisephysiologistsundermedical oversight. Participants:Sedentaryorminimallyactivenon-treatmentseekingcannabis-dependentadults(n=12,age2563years,8 females) met criteria for primary cannabis dependence using the Substance Abuse module of the Structured Clinical InterviewforDSM-IV(SCID). Measurements:Self-reporteddrugusewasassessedfor1-weekbefore,during,and2-weeksafterthestudy.Participants viewedvisualcannabiscuesbeforeandafterexerciseinconjunctionwithassessmentofsubjectivecannabiscravingusing the