基于巯基-炔的“点击”化学研究进展.pdfVIP

学兔兔 化 工 进 展 · l982· CHEMICAL INDUSTRY AND ENGINEERING PROGRESS 2011年第30卷第9期 基于巯基．炔的“点击化学研究进展 蔡 雷，熊兴泉，唐忠科，徐源鸿 (华侨大学材料科学与工程学院，福建省高校功能材料重点实验室，福建 厦门 361021) 摘 要：“点击”化学由于具有原料易得、反应条件温和、高的产率和选择性等特点，已受到人们的广泛关注。 巯基一炔反应是近年来被证实的一种新型 “点击”反应，具有简单、高效以及通用等特性。本文综述了 “点击” 化学的定义、特点、发展历程及应用，系统介绍了巯基一炔 “点击”反应的机理及其在制备功能分子和表面修饰 方面的研究进展，主要包括树枝状聚合物、超支化聚合物、网状聚合物、功能材料等的制备和材料的表面改性。 最后对巯基一炔 “点击”反应的发展前景进行了展望。 关键词：“点击”化学；巯基一炔反应；功能聚合物；表面修饰 中图分类号：O 636．1 文献标志码：A 文章编号：1000—6613(2011)09—1982—08 Research progress of thiol-yne click chemistry CAILei，XIONGXingquan，TANGZhongke，XUYuanhong (College of Materials Science and Engineering，Huaqiao University，The Key Laboratory for Functional Materials of Fujian Higher Education，Xiamen 361021，Fujian，China) Abstract： Click chemiswy has already received extensive attention owing to its obvious characteristics，such as readily available starting materials，moderate reaction conditions，high yields and selectivity．Thiol—yne coupling reaction has been recently demonstrated as a novel click reaction， owning to the features of simplicity，high efficiency and versatility，moderate reaction conditions，and a single product．Herein，the definition，characteristics，history as well as applications of click chemistry are reviewed．The mechanism of thiol—yne reaction and the advance in the preparation of functional polymers and surface modification based on this reaction are discussed，including not only synthesis of dendrimers，hyperbranched polymers，networks，functional materials，biomolecules and supramolecules，but also surface modification of