Evaluation of a Multicore-Optimized Implementation for Tomographic Reconstruction 英文参考文献.docVIP
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Evaluation of a Multicore-Optimized Implementation for Tomographic Reconstruction 英文参考文献
EvaluationofaMulticore-OptimizedImplementationfor
TomographicReconstruction
Jose-IgnacioAgulleiro1,Jose′ Jesu′sFerna′ndez2*
1SupercomputingandAlgorithmsgroup,UniversityofAlmer?′a,Almer?′a,Spain,2NationalCentreforBiotechnology,NationalResearchCouncil(CNB-CSIC),Madrid,Spain
Abstract
Tomography allows elucidation of the three-dimensional structure of an object from a set of projection images. In life
sciences,electronmicroscopetomographyisprovidinginvaluableinformationaboutthecellstructureataresolutionof
afewnanometres.Here,largeimagesarerequiredtocombinewidefieldsofviewwithhighresolutionrequirements.The
computationalcomplexityofthealgorithmsalongwiththelargeimagesizethenturnstomographicreconstructioninto
acomputationallydemandingproblem.Traditionally,high-performancecomputingtechniqueshavebeenappliedtocope
with such demands on supercomputers, distributed systems and computer clusters. In the last few years, the trend has
turnedtowardsgraphicsprocessingunits(GPUs).Herewepresentadetaileddescriptionandathoroughevaluationofan
alternativeapproachthatreliesonexploitationofthepoweravailableinmodernmulticorecomputers.Thecombinationof
single-corecodeoptimization,vectorprocessing,multithreadingandefficientdiskI/Ooperationssucceedsinprovidingfast
tomographicreconstructionsonstandardcomputers.TheapproachturnsouttobecompetitivewiththefastestGPU-based
solutionsthusfar.
Citation: Agulleiro J-I, Ferna′ndez JJ (2012) Evaluation of a Multicore-Optimized Implementation for Tomographic Reconstruction. PLoS ONE 7(11): e48261.
doi:10.1371/journal.pone.0048261
Editor:FriedrichFrischknecht,UniversityofHeidelbergMedicalSchool,Germany
ReceivedJuly18,2012;AcceptedSeptember20,2012;PublishedNovember6,2012
Copyright:?2012Agulleiro,Ferna′ndez.Thisisanopen-accessarticledistributedunderthetermsoftheCreativeCommonsAttributionLicense,whichpermits
unrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalauthorandsourcearecredited.
Funding: Funding provided by the Spanish Ministry of
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