Evolutionary Convergence and Nitrogen Metabolism in Blattabacterium strain Bge, Primary Endosymbiont of the Cockroach Blattella germanica 英文参考文献.docVIP
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Evolutionary Convergence and Nitrogen Metabolism in Blattabacterium strain Bge, Primary Endosymbiont of the Cockroach Blattella germanica 英文参考文献
EvolutionaryConvergenceandNitrogenMetabolismin
BlattabacteriumstrainBge,PrimaryEndosymbiontofthe
CockroachBlattellagermanica
MariaJ.Lo′pez-Sa′nchez1,AlexanderNeef1,2,JuliPereto′1,2,3,RafaelPatin?o-Navarrete1 ,Miguel
Pignatelli1,2,4,AmparoLatorre1,2,4,5,Andre′sMoya1,2,4,5
*
1InstitutCavanillesdeBiodiversitatiBiologiaEvolutiva,UniversitatdeVale`ncia, Vale`ncia,Spain,2CIBERenEpidemiolog?′aySaludPu′blica(CIBEResp),Barcelona,Spain,
3DepartamentdeBioqu?′micaiBiologiaMolecular,UniversitatdeVale`ncia,Vale`ncia,Spain,4CentroSuperiordeInvestigacio′nenSaludPu′blica(CSISP),Vale`ncia, Spain,
5DepartamentdeGene`tica, UniversitatdeVale`ncia,Vale`ncia, Spain
Abstract
Bacterialendosymbiontsofinsectsplayacentralroleinupgradingthedietoftheirhosts.Incertaincases,suchasaphids
andtsetse flies,endosymbionts complementthemetabolic capacity ofhostsliving on nutrient-deficient diets,while the
bacteriaharboredbyomnivorouscarpenterantsareinvolvedinnitrogenrecycling.Inthisstudy,wedescribethegenome
sequence and inferred metabolism of Blattabacterium strain Bge, the primary Flavobacteria endosymbiont of the
omnivorousGermancockroachBlattellagermanica.Throughcomparativegenomicswithotherinsectendosymbiontsand
free-livingFlavobacteriawerevealthatBlattabacteriumstrainBgesharesthesamedistributionoffunctionalgenecategories
only withBlochmannia strains, the primary Gamma-Proteobacteria endosymbiont of carpenter ants. This is a remarkable
example of evolutionary convergence during the symbiotic process, involving very distant phylogenetic bacterial taxa
withinhostsfeedingonsimilardiets.Despitethissimilarity,differentnitrogeneconomystrategieshaveemergedineach
case.Bothbacterialendosymbiontscodeforureasebutdisplaydifferentmetabolicfunctions:Blochmanniastrainsproduce
ammonia from dietary urea and then use it as a source of nitrogen, whereas Blattabacterium strain Bge codes for the
completeureacyclethat,incombinationwithurease,producesammoniaasanendproduct.Notonlydoesthecockroach
endosy
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