Fine Mapping of Five Loci Associated with Low-Density Lipoprotein Cholesterol Detects Variants That Double the Explained Heritability 英文参考文献.docVIP

下载本文档

3
0
约5.08万字
约 10页
2017-05-11 发布于上海
举报
版权申诉

Fine Mapping of Five Loci Associated with Low-Density Lipoprotein Cholesterol Detects Variants That Double the Explained Heritability 英文参考文献.doc

1、本文档共10页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
8、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Fine Mapping of Five Loci Associated with Low-Density Lipoprotein Cholesterol Detects Variants That Double the Explained Heritability 英文参考文献

FineMappingofFiveLociAssociatedwithLow-Density LipoproteinCholesterolDetectsVariantsThatDouble theExplainedHeritability SerenaSanna1.*,BingshanLi2.,AntonellaMulas1.,CarloSidore1,2,3,HyunM.Kang2,AnneU.Jackson2, MariaGraziaPiras1,GianlucaUsala1,GiuseppeManinchedda4,AlessandroSassu4,FabrizioSerra4 ,Maria AntoniettaPalmas4,WilliamH.Wood III5,IngerNj?lstad6,MarkkuLaakso7,KristianHveem8 ,Jaakko Tuomilehto9,10,11,TimoA.Lakka12,13,RainerRauramaa13,MichaelBoehnke2,FrancescoCucca1,3, ManuelaUda1,DavidSchlessinger14,RamaiahNagaraja14,Gonc?aloR.Abecasis2* 1Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Italy, 2Department of Biostatistics, Center for Statistical Genetics, UniversityofMichigan,AnnArbor,Michigan,UnitedStatesofAmerica,3DipartimentodiScienzeBiomediche,Universita` diSassari,Sassari,Italy,4ShardnaLifeSciences, Pula,Italy,5GeneExpressionandGenomicsUnit,ResearchResourcesBranch,NationalInstituteonAging,Baltimore,Maryland,UnitedStatesofAmerica,6Departmentof Community Medicine, Faculty of Health Sciences, University of Tromso, Tromso, Norway, 7Department of Medicine, University of Eastern Finland, Kuopio, Finland, 8DepartmentofPublicHealth,FacultyofMedicine,NorwegianUniversityofScienceandTechnology,Trondheim,Norway,9DiabetesPreventionUnit,NationalInstitute forHealthandWelfare,Helsinki,Finland,10HjeltInstitute,DepartmentofPublicHealth,UniversityofHelsinki,Helsinki,Finland,11SouthOstrobothniaCentralHospital, Seinajoki, Finland, 12Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio, Finland, 13Kuopio Research Institute of Exercise Medicine, Kuopio, Finland,14LaboratoryofGenetics,NationalInstituteonAging,Baltimore,Maryland,UnitedStatesofAmerica Abstract Complex trait genome-wide association studies (GWAS) provide an efficient strategy for evaluating large numbers of common variants in large numbers of individuals and for identifying trait-associated variants. Nevertheless, GWAS often leavemuchoft