Five-Year Prognosis in an Incident Cohort of People Presenting with Acute Myocardial Infarction 英文参考文献.docVIP

下载本文档

3
0
约3.76万字
约 7页
2017-05-11 发布于上海
举报
版权申诉

Five-Year Prognosis in an Incident Cohort of People Presenting with Acute Myocardial Infarction 英文参考文献.doc

1、本文档共7页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
8、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Five-Year Prognosis in an Incident Cohort of People Presenting with Acute Myocardial Infarction 英文参考文献

Five-YearPrognosisinanIncidentCohortofPeople PresentingwithAcuteMyocardialInfarction ColinR.Simpson1*,BrianS.Buckley2,DavidJ.McLernon3,AzizSheikh1,AndrewMurphy2,PhilipC. Hannaford4 1eHealthResearchGroup,CentreforPopulationHealthSciences,TeviotPlace,MedicalSchool,TheUniversityofEdinburgh,Edinburgh,UnitedKingdom,2Departmentof GeneralPractice,NationalUniversityofIreland,Galway,Ireland,3MedicalStatisticsTeam,SectionofPopulationHealth,UniversityofAberdeen,Foresterhill,Aberdeen, UnitedKingdom,4CentreofAcademicPrimaryCare,UniversityofAberdeen,Foresterhill,Aberdeen,UnitedKingdom Abstract Background:FollowinganAMI,itisimportantforpatientsandtheirphysicianstoappreciatethesubsequentriskofdeath, andthepotentialbenefitsofinvasivecardiacproceduresandsecondarypreventivetherapy.Studies,to-date,havefocused largelyonhigh-riskpopulations.Wewishedtodeterminetheriskofdeathinapopulation-derivedcohortof2,887patients afterafirstacutemyocardialinfarction(AMI). Methods: Logistic regression and survival analysis were conducted to investigate the effect of different baseline characteristics,pharmacologicaltherapiesandrevascularizationproceduresoncoronaryheartdisease(CHD)andall-cause mortalityoutcomes. Results: Within five years 44.4% of patients died (27.1% short-term [,30 days] and 23.7% longer-term [$30 days]). Percutaneoustransluminalcoronaryangioplasty(Adjusted HazardsRatio(AHR)=0.49,95%ConfidenceInterval(CI)0.26– 0.93),b-blockers(AHR=0.58,95%CI0.46–0.74)andstatins(AHR=0.60,95%CI0.47–0.77)wereallassociatedwithsignificant reductionsinlonger-termCHD-relatedmortality.However,notallpatientsreceivedsecondarypreventivetherapy(8.7%). Diabetes (AHR=1.83, 95%CI 1.43–2.34), stroke (AHR=1.73, 95%CI 1.35–2.22), heart failure (AHR=1.69, 95%CI 1.28–2.22), smoking(AHR=1.72,95%CI1.18–2.51)andobesity(.30kg/m2;AHR=1.39,95%CI1.01–1.90)increasedtheriskoflonger- termmortalityindependentofotherriskfactors. Conclusions: It is encouraging that the coronary procedure PTCA and pharmacological secondary preventi