甲型AH1N1病毒流感合并重症肺炎临床特点初步分析.pdfVIP

第46 卷第5 期 哈尔滨医科大学学报 Vo1. 46 ,No.5 2012 年 10 月 JOURNAL OF HARBIN MEDICAL UNIVERSITY Oct. , 2012 499 甲型 A/HINl 病毒流感合并重症肺炎 临床特点初步分析 王威l ，李 5~1 ，陈复辉2 ，陈宏2\ 曲波3 ，鲍永霞2 (1.哈尔滨医科大学附属第二医院内分泌科;2. 呼吸内科;3. 消化内科，黑龙江哈尔滨 15∞81) [摘要] 曲曲曲 初步分析甲型 AlHINI 流感病毒合并重症肺炎的临床特点。方放 收集 21 例入院确 诊的甲型 AlHINI 流感病毒合并重症肺炎患者的数据并进行分析。结票 所有甲流患者通过咽拭子 real-time PCR 确诊。血常规提示自细胞不升高或降低，动脉血气反映 I 型呼衰的特点，细菌培养阴性，血 浆酶学检测显示肝功能和心脏功能变化，胸部 CT 提示肺部病变进展迅猛。结份 起病急，进展快是甲 流合并肺炎的发病特点，具有易累及肝脏、心脏器官的特点。 [关键词] 甲型 AlH1N1 流感;肺炎;临床特点 [中图分类号]R51 1. 7 [文献标识码]A [文章编号] 1∞0-1905(2012)05 -0499 -03 Preliminary analysis on clinical features of i nf1uenza A/HINl infection com- Iicated with severe pneumonia 1 1 2 WANG Wei , LI Qiang , CHEN Fu-hui , CHEN Hon矿， QU B0 3 , BAO Yong-xii ( 1. Department 01 Endocrinology; 2. Respirα， tory Department; 3. Depαrtment 01 Gastroenterology , The Second A.fJ♀liated Hospital 01 H，αrbin Medical University , Hα， rbin 150081 , Chinα) Abstract: Objective To investigate clinical features of inf1uenza A/Hl Nl infection with se- vere pneumonia. 岛1:ethods The data from 21 pneumonia hospitalized cases with A/Hl Nl vi- rus infection were collected and analyzed. Results All the patients with A /Hl Nl infection were confirmed by airway secretion with real-time PCR methods. The results of blood routine showed no increased or decreased white blood cells. ArteIγblood gas analysis represented char- acteristics of type 1 respiratory failure. Blood or sputum bacteria culture was negative. Serum enzyme detection .indicated abnormalliver and heart function. Chest CT scan showed extensive multiple lobular infiltrates. Conclusion Human A/Hl Nl infection with secondary pulmonary infiltration developed quickly , ref1ecting i叮ured liver ànd heart function. Key words: A/Hl Nl inf1u