原创力文档Laropiprant Attenuates EP3 and TP Prostanoid Receptor-Mediated Thrombus Formation 英文参考文献.docVIP
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Laropiprant Attenuates EP3 and TP Prostanoid Receptor-Mediated Thrombus Formation 英文参考文献
LaropiprantAttenuatesEP3andTPProstanoidReceptor-
MediatedThrombusFormation
SoniaPhilipose1,ViktoriaKonya1,MirjanaLazarevic1,LisaM.Pasterk1,GuntherMarsche1,SasaFrank2,
BernhardA.Peskar1,AkosHeinemann1*,RufinaSchuligoi1
1InstituteofExperimentalandClinicalPharmacology,MedicalUniversityofGraz,Graz,Austria,2InstituteofMolecularBiologyandBiochemistry,MedicalUniversityof
Graz,Graz,Austria
Abstract
The use of the lipid lowering agent niacin is hampered by a frequent flush response which is largely mediated by
prostaglandin(PG)D2.Therefore,concomitantadministrationoftheD-typeprostanoid(DP)receptorant
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