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Neurocysticercosis, a Persisting Health Problem in Mexico 英文参考文献
Neurocysticercosis,aPersistingHealthProblemin
Mexico
Agne`sFleury1,2*,JaelMorenoGarc?′a1,PaulinaValdezAguerrebere1,Mar?′adeSayveDura′n1 ,Paola
BecerrilRodr?′guez1,CarlosLarralde2,EddaSciutto2
1InstitutoNacionaldeNeurolog?′ayNeurocirug?′a,MexicoCity,Me′xico,2InstitutodeInvestigacionesBiome′dicas,UniversidadNacionalAuto′nomadeMe′xico,MexicoCity,
Me′xico
Abstract
Background:TheongoingepidemiologicaltransitioninMexicominimizestherelativeimpactofneurocysticercosis(NC)on
publichealth.However,harddataonthediseasefrequencyarenotavailable.
Methodology:AllclinicalrecordsfrompatientsadmittedintheInstitutoNacionaldeNeurologiayNeurocirugia(INNN)at
MexicoCityin1994 and2004 wererevised. ThefrequenciesofhospitalizedNCpatients inneurology,neurosurgery and
psychiatry services, as well as NC mortality from 1995 through 2009, were retrieved. Statistical analyses were made to
evaluate possible significant differences in frequencies of NC patients’ admission between 1994 and 2004, and in yearly
frequenciesofNCpatients’hospitalizationanddeathbetween1995and2009.
PrincipalFindings:NCfrequencyinINNNisnotsignificantlydifferentin1994and2004.Betweenthesetwoyears,clinical
severity of the cases diminished and the proportion of patients living in Mexico City increased. Yearly frequencies of
hospitalizationinneurologyandpsychiatryserviceswerestable,whilefrequenciesofhospitalizationinneurosurgeryservice
andmortalitysignificantlydecreasedbetween1995and2009.
Conclusions: Our findings show a stable tendency of hospital cases during the last decade that should encourage to
redoubleeffortstocontrolthisancientdisease.
Citation:FleuryA,MorenoGarc?′aJ,ValdezAguerrebereP,deSayveDura′nM,BecerrilRodr?′guezP,etal.(2010)Neurocysticercosis,aPersistingHealthProblemin
Mexico.PLoSNeglTropDis4(8):e805.doi:10.1371/journal.pntd.0000805
Editor:PatriciaP.Wilkins,CenterforDiseaseControl,UnitedStatesofAmerica
ReceivedApril2,2010;AcceptedJuly27,2010;PublishedAugust24,2010
Copyright: ? 2010 Fleury et al. This is an op
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