Obstructive sleep apnoea a cause of chronic cough 英文参考文献.docVIP

Cough BioMedCentral Research Open Access Obstructive sleep apnoea: a cause of chronic cough Surinder S Birring*3, Alvin J Ing1, Kevin Chan1, Gavina Cossa1, Sergio Matos2, Michael DL Morgan2 and Ian D Pavord2 Address: 1Respiratory Investigation Unit, Concord Hospital, Sydney, Australia, 2Institute for Lung Health, Department of Respiratory Medicine, Glenfield Hospital, Leicester, UK and 3Department of Respiratory Medicine, Kings College Hospital, London, UK Email: Surinder S Birring* - surinder.birring@kch.nhs.uk; Alvin J Ing - ajing@.au; Kevin Chan - kev.the.man@.au; Gavina Cossa - cossag@.au; Sergio Matos - aleixomatos@; Michael DL Morgan - mike.morgan@uhl-tr.nhs.uk; Ian D Pavord - ian.pavord@uhl-tr.nhs.uk * Corresponding author Published: 2 July 2007 Received: 19 March 2007 Accepted: 2 July 2007 Cough 2007, 3:7 doi:10.1186/1745-9974-3-7 This article is available from: /content/3/1/7 ? 2007 Birring et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Chronic cough is a common reason for presentation to both general practice and respiratory clinics. In up to 25% of cases, the cause remains unclear after extensive investigations. We report 4 patients presenting with an isolated chronic cough who were subsequently found to have obstructive sleep apnoea. The cough improved rapidly with nocturnal continuous positive airway pressure therapy. Further studies are required to investigate the prevalence of coexistence of these common conditions. Background multiple courses of antibiotics, which were unhelpful. He also complained of mild dyspnoea on climbing hills but no wheezing. He had longstanding left nasal congestion without post-nasal drip following a broken nose in child- hood and