Optimization of a crossing system using mate selection 英文参考文献.docVIP

Optimization of a crossing system using mate selection 英文参考文献.doc

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Optimization of a crossing system using mate selection 英文参考文献

Genet.Sel.Evol.38(2006)147-165 c INRA,EDPSciences,2006 DOI:10.1051/gse:2005033 147 Originalarticle Optimizationofacrossingsystem usingmateselection YongjunLia,b?,JuliusH.J.vanderWerfa,BrianP.Kinghorna,c a SchoolofRuralScienceandAgriculture,UniversityofNewEngland, ArmidaleNSW2351,Australia b c InstituteofAnimalScience,JilinAgriculturalUniversity,Changchun130118,P.R.China SygenChairofGeneticInformationSystems,theInstituteofGeneticandBioinformatics, UniversityofNewEngland,Armidale,NSW2351,Australia (Received4May2005;accepted21October2005) Abstract –A simple model based on one single identi?ed quantitative trait locus (QTL) in atwo-way crossingsystemwasusedtodemonstratethepower of mateselectionalgorithms asanatural meansof opportunistic linedevelopment for optimizationof crossbreeding pro- gramsovermultiplegenerations.Mateselectionautomaticallyinvokesdivergent selectionin twoparentallinesforanover-dominantQTLandincreasedfrequencyofthefavorablealleleto- ward?xationinthesire-lineforafully-dominantQTL.Itwasconcludedthatanoptimalstrategy oflinedevelopmentcouldbefoundbymateselectionalgorithmsforagivensetofparameters suchasgeneticmodelofQTL,breedingobjectiveandinitialfrequencyofthefavorableallele inthebase populations, etc. Thesameframework could be used inother scenarios, such as programsinvolvingcrossingtoexploitbreede?ectsandheterosis.Incontrasttoclassicalindex selection,thisapproachtomateselectioncanoptimizelong-termresponses. quantitativetraitlocus/optimalutilization/two-waycrossingsystem/mateselection 1. INTRODUCTION Crossbreedingisthematingofsiresofonebreedorbreedcombinationto damsofanotherbreedorbreedcombination[4].Crossbreedingiscarriedout forseveralreasons.Itisusedtodevelopnewbreedsortypesfromfoundation purebreds and to introgress genes and characteristics from one breed to an- other[6,25].Itiswidelyusedincommercialanimalproductionasameansof exploitingheterosis[5,21,23].Crossbreedingisalsovaluablefortheaverag- ingofbreede?ects,forexamplewhenananimalofin

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