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Optimization of a crossing system using mate selection 英文参考文献
Genet.Sel.Evol.38(2006)147-165
c INRA,EDPSciences,2006
DOI:10.1051/gse:2005033
147
Originalarticle
Optimizationofacrossingsystem
usingmateselection
YongjunLia,b?,JuliusH.J.vanderWerfa,BrianP.Kinghorna,c
a
SchoolofRuralScienceandAgriculture,UniversityofNewEngland,
ArmidaleNSW2351,Australia
b
c
InstituteofAnimalScience,JilinAgriculturalUniversity,Changchun130118,P.R.China
SygenChairofGeneticInformationSystems,theInstituteofGeneticandBioinformatics,
UniversityofNewEngland,Armidale,NSW2351,Australia
(Received4May2005;accepted21October2005)
Abstract –A simple model based on one single identi?ed quantitative trait locus (QTL) in
atwo-way crossingsystemwasusedtodemonstratethepower of mateselectionalgorithms
asanatural meansof opportunistic linedevelopment for optimizationof crossbreeding pro-
gramsovermultiplegenerations.Mateselectionautomaticallyinvokesdivergent selectionin
twoparentallinesforanover-dominantQTLandincreasedfrequencyofthefavorablealleleto-
ward?xationinthesire-lineforafully-dominantQTL.Itwasconcludedthatanoptimalstrategy
oflinedevelopmentcouldbefoundbymateselectionalgorithmsforagivensetofparameters
suchasgeneticmodelofQTL,breedingobjectiveandinitialfrequencyofthefavorableallele
inthebase populations, etc. Thesameframework could be used inother scenarios, such as
programsinvolvingcrossingtoexploitbreede?ectsandheterosis.Incontrasttoclassicalindex
selection,thisapproachtomateselectioncanoptimizelong-termresponses.
quantitativetraitlocus/optimalutilization/two-waycrossingsystem/mateselection
1. INTRODUCTION
Crossbreedingisthematingofsiresofonebreedorbreedcombinationto
damsofanotherbreedorbreedcombination[4].Crossbreedingiscarriedout
forseveralreasons.Itisusedtodevelopnewbreedsortypesfromfoundation
purebreds and to introgress genes and characteristics from one breed to an-
other[6,25].Itiswidelyusedincommercialanimalproductionasameansof
exploitingheterosis[5,21,23].Crossbreedingisalsovaluablefortheaverag-
ingofbreede?ects,forexamplewhenananimalofin
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