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Optimal Information Transfer in the Cortex through Synchronization 英文参考文献
OptimalInformationTransferintheCortexthrough
Synchronization
AndresBuehlmann1*,GustavoDeco1,2
1ComputationalNeuroscience,UniversitatPompeuFabra,Barcelona,Spain,2Institucio′ Catalanad’EstudisAvanc?ats (ICREA),Barcelona,Spain
Abstract
Inrecentexperimentalworkithasbeenshownthatneuronalinteractionsaremodulatedbyneuronalsynchronizationandthat
thismodulationdependsonphaseshiftsinneuronaloscillations.Thisresultsuggeststhatconnectionsinanetworkcanbe
shapedthroughsynchronization.Here,wetestandexpandthishypothesisusingamodelnetwork.Weusetransferentropy,
aninformationtheoreticalmeasure,toquantifytheexchangedinformation.Weshowthattransferredinformationdependson
thephaserelationofthesignal,thattheamountofexchangedinformationincreasesasafunctionofoscillationsinthesignal
andthatthespeedoftheinformationtransferincreasesasafunctionofsynchronization.Thisimpliesthatsynchronization
makesinformationtransportmoreefficient.Insummary,ourresultsreinforcethehypothesisthatsynchronizationmodulates
neuronalinteractionsandprovidefurtherevidencethatgammabandsynchronizationhasbehavioralrelevance.
Citation: Buehlmann A, Deco G (2010) Optimal Information Transfer in the Cortex through Synchronization. PLoS Comput Biol 6(9): e1000934. doi:10.1371/
journal.pcbi.1000934
Editor:KarlJ.Friston,UniversityCollegeLondon,UnitedKingdom
ReceivedMay20,2010;AcceptedAugust17,2010;PublishedSeptember16,2010
Copyright:?2010Buehlmann,Deco.Thisisanopen-accessarticledistributedunderthetermsoftheCreativeCommonsAttributionLicense,whichpermits
unrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalauthorandsourcearecredited.
Funding:TheauthorsweresupportedbytheEuropeanProject‘‘Brainsync’’andbytheSpanishResearchProjectBFU2007-61710andCONSOLIDERINGENIO2010
(‘‘Bilingualism andCognitiveNeuroscience’’).The funders had norole instudydesign,datacollectionand analysis, decisiontopublish,orpreparation of the
manuscript.
CompetingInterests:Theauthorshavedeclaredthatnocompetinginterestsexist.
*E-mail:an
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