Organ donation after circulatory death the forgotten donor 英文参考文献.docVIP

Available online /content/10/5/166 Commentary Organ donation after circulatory death: the forgotten donor? Mohamed Y Rady1, Joseph L Verheijde2 and Joan McGregor3 1Department of Critical Care Medicine, Mayo Clinic Hospital, Mayo Clinic College of Medicine, 5777 East Mayo Blvd, Phoenix, Arizona, USA, 85054 2Department of Physical Medicine and Rehabilitation, Mayo Clinic Hospital, Mayo Clinic College of Medicine, 5777 East Mayo Blvd Phoenix, Arizona, USA, 85054 3Bioethics, Policy, and Law Program, School of Philosophy and Life Sciences, Arizona State University, Box 4501, 300 East University Drive, Tempe, Arizona, USA, 85281 Corresponding author: Mohamed Y Rady, rady.mohamed@ Published: 29 September 2006 Critical Care 2006, 10:166 (doi:10.1186/cc5038) This article is online at /content/10/5/166 ? 2006 BioMed Central Ltd Abstract The transplantation community has been reorganized into 58 donation service areas (DSAs) to cover the entire country [5]. Each DSA is centered on one organ procurement organization (OPO) that facilitates the recovery and flow of transplantable organs from donor hospital(s) to regional transplant center(s) within a defined geographic location. Each of the DSAs will have to meet a target goal of 75% or higher of cadaveric organ donation rate from its affiliated hospitals. Donation after circulatory death (DCD) can be performed on neurologically intact donors who do not fulfill neurologic or brain death criteria before circulatory arrest. This commentary focuses on the most controversial donor-related issues anticipated from mandatory implementation of DCD for imminent or cardiac death in hospitals across the USA. We conducted a nonstructured review of selected publications and websites for data extraction and synthesis. The recommended 5 min of circulatory arrest does not universally fulfill the dead donor rule when applied to otherwise neurologically intact donors.