Optoelectronic Capillary Sensors in Microfluidic and Point-of-Care Instrumentation 英文参考文献.docVIP

Sensors 2010, 10, 3771-3797; doi:10.3390/s100403771 OPEN ACCESS sensors ISSN 1424-8220 /journal/sensors Review Optoelectronic Capillary Sensors in Microfluidic and Point-of-Care Instrumentation Micha? Borecki 1,*, Michael L. Korwin-Pawlowski 2, Maria Beblowska 1, Jan Szmidt 1 and Andrzej Jakubowski 1 1 Institute of Microelectronics and Optoelectronics, Warsaw University of Technology, Koszykowa 75, 00-662 Warsaw, Poland; E-Mails: beblowska@.pl (M.B.); j.szmidt@.pl (J.S.); a.jakubowski@.pl (A.J.) 2 Département d’informatique et d’ingénierie, Université du Québec en Outaouais, 101 rue Saint-Jean-Bosco, Gatineau, QC J8X 3X7, Canada; E-Mail: michael.korwin-pawlowski@uqo.ca * Author to whom correspondence should be addressed; E-Mail: borecki@.pl; Tel.: +48-22-234-7749; Fax: +48-22-628-8740. Received: 15 February 2010; in revised form: 10 March 2010 / Accepted: 30 March 2010 / Published: 14 April 2010 Abstract: This paper presents a review, based on the published literature and on the authors’ own research, of the current state of the art of fiber-optic capillary sensors and related instrumentation as well as their applications, with special emphasis on point-of-care chemical and biochemical sensors, systematizing the various types of sensors from the point of view of the principles of their construction and operation. Unlike classical fiber-optic sensors which rely on changes in light propagation inside the fiber as affected by outside conditions, optical capillary sensors rely on changes of light transmission in capillaries filled with the analyzed liquid, which opens the possibility of interesting new applications, while raising specific issues relating to the construction, materials and instrumentation of those sensors. Keywords: fiber-optic sensors; photonic sensors; optical capillaries; optical fibers; chemical sensors; optochemical sensors; capillary sensors; liquid-core sensors; hollow-core sensors; bioc