pax1-1 partially suppresses gain-of-function mutations in Arabidopsis AXR3IAA17 英文参考文献.docVIP

BMC Plant Biology BioMedCentral Research article Open Access pax1-1 partially suppresses gain-of-function mutations in Arabidopsis AXR3/IAA17 Mimi Tanimoto1,2, Jemma Jowett1,3, Petra Stirnberg1, Dean Rouse1,4 and Ottoline Leyser*1 Address: 1Department of Biology, University of York, Heslington, York, YO10 5YW, UK, 2Department of Molecular and Cellular Biology, Axelrod Building, University of Guelph, Guelph, Ontario, N1G 2W1, Canada, 3Section of Molecular and Cellular Biology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA and 4Research School of Biological Science, GPO Box 475, Canberra, ACT 2601, Australia Email: Mimi Tanimoto - htanimot@uoguelph.ca; Jemma Jowett - jjowett@; Petra Stirnberg - ps25@york.ac.uk; Dean Rouse - rouse@.au; Ottoline Leyser* - hmol1@york.ac.uk * Corresponding author Published: 12 April 2007 Received: 6 November 2006 Accepted: 12 April 2007 BMC Plant Biology 2007, 7:20 doi:10.1186/1471-2229-7-20 This article is available from: /1471-2229/7/20 ? 2007 Tanimoto et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The plant hormone auxin exerts many of its effects on growth and development by controlling transcription of downstream genes. The Arabidopsis gene AXR3/IAA17 encodes a member of the Aux/IAA family of auxin responsive transcriptional repressors. Semi-dominant mutations in AXR3 result in an increased amplitude of auxin responses due to hyperstabilisation of the encoded protein. The aim of this study was to identify novel genes involved in auxin signal transduction by screening for second site mutations that modify the axr3-1 gain-of-function phenotype. Results: We present the isolation of the partial sup