Prevalence of Anaplasma phagocytophilum infection and effect on lamb growth 英文参考文献.docVIP

Prevalence of Anaplasma phagocytophilum infection and effect on lamb growth 英文参考文献.doc

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Prevalence of Anaplasma phagocytophilum infection and effect on lamb growth 英文参考文献

Gr?vaetal.ActaVeterinariaScandinavica2011,53:30 /content/53/1/30 RESEARCH OpenAccess PrevalenceofAnaplasmaphagocytophilum infectionandeffectonlambgrowth LiseGr?va1,2*,IngridOlesen2,3,H?vardSteinshamn1andSnorreStuen4 Abstract Background:Amajorchallengeinsheepfarmingduringthegrazingseasonalongthecoastofsouth-western Norwayistick-bornefever(TBF)causedbythebacteriaAnaplasmaphagocytophilumthatistransmittedbythetick Ixodesricinus. Methods:Astudywascarriedoutin2007and2008toexaminetheprevalenceofA.phagocytophiluminfection andeffectonweaningweightinlambs.Thestudyincluded1208lambsfromfarmsinSunndalRamCircleinM?re andRomsdalCountyinMid-Norway,whereticksarefrequentlyobserved.Alllambswerebloodsampledand serumwasanalyzedbyanindirectfluorescentantibodyassay(IFA)todetermineanantibodystatus(positiveor negative)toA.phagocytophiluminfection.Weightandweightgainandpossibleeffectofinfectionwereanalyzed usingANOVAandtheMIXEDprocedureinSAS. Results:TheoverallprevalenceofinfectionwithA.phagocytophilumwas55%.Alowerweaningweightof3% (1.34kg,p0.01)wasestimatedinlambsseropositivetoanA.phagocytophiluminfectioncomparedto seronegativelambsatanaverageageof137days. Conclusions:TheresultsshowthatA.phagocytophiluminfectionhasaneffectonlambweightgain.Thestudy alsosupportpreviousfindingsthatA.phagocytophiluminfectioniswidespreadinareaswhereticksareprevalent, eveninflockstreatedprophylacticwithacaricides. Background thatchallengeswithTBFwillincreaseinNorwayinthe Tick-bornefever(TBF)isoneofthemainchallengesin comingyears. Norwegiansheepfarmingduringthegrazingseason[1]. ThemainconsequenceofanA.phagocytophiluminfec- TBFiscausedbythebacteriaAnaplasmaphagocytophi- tioninsheepistheensuingimmunosuppressionthatmay lum, transmitted by the tick Ixodes ricinus, and may lead tosecondary infections andcause bothdirect and cause direct (lamb deaths) and indirect loss (reduced indirectlosses.Directlossesofca30%lambmortalityina growth)insheepfarming.Thenormaldistribution area flock due to A. phagocytophil

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