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Prevalence of Anaplasma phagocytophilum infection and effect on lamb growth 英文参考文献
Gr?vaetal.ActaVeterinariaScandinavica2011,53:30
/content/53/1/30
RESEARCH
OpenAccess
PrevalenceofAnaplasmaphagocytophilum
infectionandeffectonlambgrowth
LiseGr?va1,2*,IngridOlesen2,3,H?vardSteinshamn1andSnorreStuen4
Abstract
Background:Amajorchallengeinsheepfarmingduringthegrazingseasonalongthecoastofsouth-western
Norwayistick-bornefever(TBF)causedbythebacteriaAnaplasmaphagocytophilumthatistransmittedbythetick
Ixodesricinus.
Methods:Astudywascarriedoutin2007and2008toexaminetheprevalenceofA.phagocytophiluminfection
andeffectonweaningweightinlambs.Thestudyincluded1208lambsfromfarmsinSunndalRamCircleinM?re
andRomsdalCountyinMid-Norway,whereticksarefrequentlyobserved.Alllambswerebloodsampledand
serumwasanalyzedbyanindirectfluorescentantibodyassay(IFA)todetermineanantibodystatus(positiveor
negative)toA.phagocytophiluminfection.Weightandweightgainandpossibleeffectofinfectionwereanalyzed
usingANOVAandtheMIXEDprocedureinSAS.
Results:TheoverallprevalenceofinfectionwithA.phagocytophilumwas55%.Alowerweaningweightof3%
(1.34kg,p0.01)wasestimatedinlambsseropositivetoanA.phagocytophiluminfectioncomparedto
seronegativelambsatanaverageageof137days.
Conclusions:TheresultsshowthatA.phagocytophiluminfectionhasaneffectonlambweightgain.Thestudy
alsosupportpreviousfindingsthatA.phagocytophiluminfectioniswidespreadinareaswhereticksareprevalent,
eveninflockstreatedprophylacticwithacaricides.
Background
thatchallengeswithTBFwillincreaseinNorwayinthe
Tick-bornefever(TBF)isoneofthemainchallengesin comingyears.
Norwegiansheepfarmingduringthegrazingseason[1].
ThemainconsequenceofanA.phagocytophiluminfec-
TBFiscausedbythebacteriaAnaplasmaphagocytophi- tioninsheepistheensuingimmunosuppressionthatmay
lum, transmitted by the tick Ixodes ricinus, and may lead tosecondary infections andcause bothdirect and
cause direct (lamb deaths) and indirect loss (reduced indirectlosses.Directlossesofca30%lambmortalityina
growth)insheepfarming.Thenormaldistribution area flock due to A. phagocytophil
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