Primary anaplastic large cell lymphoma of the breast arising in reconstruction mammoplasty capsule of saline filled breast implant after radical mastectomy for breast cancer an unusual case presentation 英文参考文献.docVIP
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Primary anaplastic large cell lymphoma of the breast arising in reconstruction mammoplasty capsule of saline filled breast implant after radical mastectomy for breast cancer an unusual case presentation 英文参考文献
Diagnostic Pathology
BioMedCentral
Case Report
Open Access
Primary anaplastic large cell lymphoma of the breast arising in
reconstruction mammoplasty capsule of saline filled breast implant
after radical mastectomy for breast cancer: an unusual case
presentation
Mona RY Bishara, Cathy Ross and Monalisa Sur*
Address: Department of Anatomical Pathology, Henderson Hospital, 711 Concession Street, ON L8V13C, Hamilton, Ontario, Canada
Email: Mona RY Bishara - mona.bishara@medportal.ca; Cathy Ross - rossca@hhsc.ca; Monalisa Sur* - surm@hhsc.ca
* Corresponding author
Published: 2 April 2009
Received: 19 January 2009
Accepted: 2 April 2009
Diagnostic Pathology 2009, 4:11
doi:10.1186/1746-1596-4-11
This article is available from: /content/4/1/11
? 2009 Bishara et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Primary non-Hodgkin lymphoma (NHL) of the breast represents 0.04–0.5% of
malignant lesions of the breast and accounts for 1.7–2.2% of extra-nodal NHL. Most primary cases
are of B-cell phenotype and only rare cases are of T-cell phenotype. Anaplastic large cell lymphoma
(ALCL) is a rare T-cell lymphoma typically seen in children and young adults with the breast being
one of the least common locations. There are a total of eleven cases of primary ALCL of the breast
described in the literature. Eight of these cases occurred in proximity to breast implants, four in
relation to silicone breast implant and three in relation to saline filled breast implant with three out
of the eight implant related cases having previous history of breast cancer treated surgically.
Adjuvant postoperative chemotherapy is given in only one case. Secondary hematological
malignancies aft
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