Prospective, randomized trial comparing fluids and dobutamine optimization of oxygen delivery in high-risk surgical patients [ISRCTN42445141] 英文参考文献.docVIP

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Prospective, randomized trial comparing fluids and dobutamine optimization of oxygen delivery in high-risk surgical patients [ISRCTN42445141] 英文参考文献.doc

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Prospective, randomized trial comparing fluids and dobutamine optimization of oxygen delivery in high-risk surgical patients [ISRCTN42445141] 英文参考文献

Available online /content/10/3/R72 Research Open Access Vol 10 No 3 Prospective, randomized trial comparing fluids and dobutamine optimization of oxygen delivery in high-risk surgical patients [ISRCT Suzana M Lobo, Francisco R Lobo, Carlos A Polachini, Daniela S Patini, Adriana E Yamamoto, Neymar E de Oliveira, Patricia Serrano, Helder S Sanches, Marco A Spegiorin, Marcio M Queiroz, Antonio C Christiano Jr, Elisangela F Savieiro, Paula A Alvarez, Silvia P Teixeira and Geni S Cunrath Division of Critical Care Medicine, Departments of Internal Medicine, Anesthesiology and Surgery, Medical School – FUNFARME and Hospital de Base, S?o José do Rio Preto, S?o Paulo, Brazil Corresponding author: Suzana M Lobo, suzanalobo@ Received: 16 Mar 2006 Accepted: 6 Apr 2006 Published: 12 May 2006 Critical Care 2006, 10:R72 (doi:10.1186/cc4913) This article is online at: /content/10/3/R72 ? 2006 Lobo et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Preventing perioperative tissue oxygen debt contributes to a better postoperative recovery. Whether the beneficial effects of fluids and inotropes during optimization of Results The cardiovascular depression was an important component in the perioperative period in this group of patients. Cardiovascular complications in the postoperative period occurred significantly more frequently in the volume group (13/ 25, 52%) than in the dobutamine group (4/25, 16%) (relative risk, 3.25; 95% confidence interval, 1.22–8.60; P 0.05). The 60-day mortality rates were 28% in the volume group and 8% in the dobutamine group (relative risk, 3.00; 95% confidence interval, 0.67–13.46; not significant). the oxygen delivery index (DO I) in hig