Proteome analysis of schizophrenia patients Wernickes area reveals an energy metabolism dysregulation 英文参考文献.docVIP

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Proteome analysis of schizophrenia patients Wernickes area reveals an energy metabolism dysregulation 英文参考文献.doc

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Proteome analysis of schizophrenia patients Wernickes area reveals an energy metabolism dysregulation 英文参考文献

BMC Psychiatry BioMedCentral Research article Open Access Proteome analysis of schizophrenia patients Wernickes area reveals an energy metabolism dysregulation Daniel Martins-de-Souza*1,2,3, Wagner F Gattaz1, Andrea Schmitt4, José C Novello2, Sérgio Marangoni2, Christoph W Turck3 and Emmanuel Dias-Neto1,5 Address: 1Laboratório de Neurociências, Instituto de Psiquiatria, Faculdade de Medicina da USP, Rua Dr. Ovídio Pires de Campos, no 785, S?o Paulo, SP, CEP 05403-010, Brazil, 2Max Planck Institute of Psychiatry, Kraepelinstrasse 2, D-80804, Munich, Germany, 3Departamento de Bioquímica, Instituto de Biologia, UNICAMP, CEP 13083-970, Campinas, SP, Brazil, 4Department of Psychiatry, Von Siebold Str. 5, University of Goettingen, 37075 Goettingen, Germany and 5University of Texas, MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, Texas, USA Email: Daniel Martins-de-Souza* - martins@mpipsykl.mpg.de; Wagner F Gattaz - gattaz@usp.br; Andrea Schmitt - aschmit@gwdg.de; José C Novello - jcn@unicamp.br; Sérgio Marangoni - marango@unicamp.br; Christoph W Turck - turck@mpipsykl.mpg.de; Emmanuel Dias- Neto - emmanuel@usp.br * Corresponding author Published: 30 April 2009 Received: 13 October 2008 Accepted: 30 April 2009 BMC Psychiatry 2009, 9:17 doi:10.1186/1471-244X-9-17 This article is available from: /1471-244X/9/17 ? 2009 Martins-de-Souza et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Schizophrenia is likely to be a consequence of DNA alterations that, together with environmental factors, will lead to protein expression differences and the ultimate establishment of the illness. The superior temporal gyrus is implicated in schizophrenia and executes functions such as the processing