Recent Development in Optical Fiber Biosensors 英文参考文献.docVIP

Sensors 2007, 7, 797-859 sensors ISSN 1424-8220 ? 2007 by MDPI /sensors Review Recent Development in Optical Fiber Biosensors María Espinosa Bosch 1, Antonio Jesús Ruiz Sánchez 2, Fuensanta Sánchez Rojas 3,* and Catalina Bosch Ojeda 3 1 Department of Pharmacy, General Hospital, University Hospital Virgen del Rocío, Manuel Siurot s/n, 41013, Sevilla, Spain; E-mail: (maria.espinosa.sspa@juntadeandalucia.es) 2 Department of Organic Chemistry, Faculty of Sciences, University of Málaga, Campus Teatinos s/n, 29071, Málaga, Spain; E-mail: (ajruizs@uma.es) 3 Department of Analytical Chemistry, Faculty of Sciences, University of Málaga, Campus Teatinos s/n, 29071, Málaga, Spain; E-mail: (fsanchezr@uma.es). E-mail: (cbosch@uma.es) * Author to whom correspondence should be addressed. Phone: +34-95-213-7393, Fax: +34-95-213- 2000, E-mail: fsanchezr@uma.es Received: 21 May 2007 / Accepted: 1 June 2007 / Published: 4 June 2007 Abstract: Remarkable developments can be seen in the field of optical fibre biosensors in the last decade. More sensors for specific analytes have been reported, novel sensing chemistries or transduction principles have been introduced, and applications in various analytical fields have been realised. This review consists of papers mainly reported in the last decade and presents about applications of optical fiber biosensors. Discussions on the trends in optical fiber biosensor applications in real samples are enumerated. Keywords: Optical fiber, biosensor, applications, review 1. Introduction Biosensor development is driven by the continuous need for simple, rapid, and continuous in-situ monitoring techniques in a broad range of areas, e.g. medical, pharmaceutical, environmental, defense, bioprocessing, or food technology. Biosensors make use of biological components in order to sense a species of interest (which by itself need not be a “biospecies”). On the other side, chemical sensors not using a b