Review of Cancer Nanotechnology Methods and Protocols (Methods in Molecular Biology) by Stephen R. Grobmyer (Editor), Brij M. Moudgil (Editor) 英文参考文献.docVIP

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Review of Cancer Nanotechnology Methods and Protocols (Methods in Molecular Biology) by Stephen R. Grobmyer (Editor), Brij M. Moudgil (Editor) 英文参考文献.doc

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Review of Cancer Nanotechnology Methods and Protocols (Methods in Molecular Biology) by Stephen R. Grobmyer (Editor), Brij M. Moudgil (Editor) 英文参考文献

SteinmetzBioMedicalEngineeringOnLine2010,9:55 /content/9/1/55 BOOK REVIEW OpenAccess Reviewof“CancerNanotechnology:Methodsand Protocols(MethodsinMolecularBiology)”by StephenR.Grobmyer(Editor),BrijM.Moudgil (Editor) NicoleFSteinmetz Correspondence:nicole. Abstract steinmetz@ DepartmentofBiomedical Engineering,CaseWesternReserve University,CaseCenterforImaging Research,11100EuclidAve., Cleveland,OH,44106,USA Cancerremainsoneoftheleadingcausesofdeath.Researchandresultingtechnolo- gieshavecontributedtorisingnumbersofcancersurvivors.Cancernanotechnology isanovelandburgeoningfieldwiththepromisetoopenthedoorforthedevelop- mentofimprovedcancertherapiesanddetectionmethods.Cancernanotechnology hasthepotentialtobecomeclinicalreality. Bookdetails “CancerNanotechnology:MethodsandProtocols(MethodsinMolecular Biology)”byStephenR.Grobmyer(Editor),BrijM.Moudgil(Editor) Hardcover:366pages Publisher:HumanaPress;1stEdition.edition(March16,2010) Language:English ISBN-10:1607616084 ISBN-13:978-1607616085 BookReview Cancer remains one of the leading causes of death. In 2009 562,340 fatalities were reportedintheUS.Cancerriskfactorsincludegenetics,environmentalexposures(che- micals, infectious agents, radiation) as well as behaviors, and food choices. Research andresultingtechnologieshavecontributedtorisingnumbersofcancersurvivors.In 2009,11.4millioncancersurvivorshavebeenreportedintheUS;1.6millionofthese have survived cancer for more than 20 years (American Association for Cancer Research). High-throughput screening methods and databases contribute to a better understandingofthedisease,earlierdetection,andimprovedtherapies. Still, current detection methods do not reach the sensitivity required and che- motherapiesaregenerallynottargetedtothesiteofdisease,resultinginundesiredside effects. Thegoalofresearchers istodeveloptargetedimagingmodalitieswithhigher signal-to-noise ratios and targeted devices for localized drug-delivery for improved efficacyandreducedadverseeffects. Advancesinnan