Review of Gene Regulation and Metabolism edited by Julio Collado-Vides and Ralf Hofest？dt 英文参考文献.docVIP

BioMedical Engineering OnLine BioMedCentral Book review Open Access Review of Gene Regulation and Metabolism edited by Julio Collado-Vides and Ralf Hofest?dt Francisco Azuaje* Address: Computer Science Research Institute, University of Ulster, Jordanstown, Co. Antrim, BT37 0QB, Northern Ireland, UK Email: Francisco Azuaje* - fj.azuaje@ulster.ac.uk * Corresponding author Published: 08 August 2005 Received: 02 August 2005 Accepted: 08 August 2005 BioMedical Engineering OnLine 2005, 4:47 doi:10.1186/1475-925X-4-47 This article is available from: /content/4/1/47 ? 2005 Azuaje; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Book details Readers would have benefited from an introductory chap- ter to overview fundamental biological concepts and problems. However, this is partially compensated by some chapters, which adequately present basic concepts and motivation necessary to approach specific applica- tions such as DNA regulatory motif discovery. Collado-Vides J, Hofest?dt R, (editors): Gene Regulation and Metabolism: Postgenomic Computational Approaches Cam- bridge, Massachusetts: The MIT Press; 2002. 295 pages, ISBN 0-262-03297-X The inference, analysis and integration of networks of genes and products are fundamental goals of post- genomic research. Over the past few years several data- and knowledge-driven computational approaches have been proposed, which have provided relevant insights into the informational complexity and function of some of such networks in different organisms. Gene Regulation and Metabolism probably represents one of the first books attempting to discuss essential computational concepts, methods and applications in