Semi-automatic algorithm for construction of the left ventricular area variation curve over a complete cardiac cycle 英文参考文献.docVIP

Semi-automatic algorithm for construction of the left ventricular area variation curve over a complete cardiac cycle 英文参考文献.doc

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Meloetal.BioMedicalEngineeringOnLine2010,9:5 /content/9/1/5 RESEARCH OpenAccess Semi-automaticalgorithmforconstructionofthe leftventricularareavariationcurveovera completecardiaccycle SalvadorAMeloJúnior1,BrunoMacchiavello2*,MarcelinoMAndrade3,Jo?oLACarvalho1,3,HervaldoSCarvalho1,4, DanielFVasconcelos4,PedroABerger2,AdsonFdaRocha1,FranciscoAONascimento1 *Correspondence: bruno@image.unb.br 2DepartmentofComputerScience, UniversityofBrasília,Brasília,DF, Brazil Abstract Background:Two-dimensionalechocardiography(2D-echo)allowstheevaluationof cardiacstructuresandtheirmovements.Awiderangeofclinicaldiagnosesarebased ontheperformanceoftheleftventricle.Theevaluationofmyocardialfunctionis typicallyperformedbymanualsegmentationoftheventricularcavityinaseriesof dynamicimages.Thisprocessislaboriousandoperatordependent.Theautomatic segmentationoftheleftventriclein4-chamberlong-axisimagesduringdiastoleis troublesome,becauseoftheopeningofthemitralvalve. Methods:Thisworkpresentsamethodforsegmentationoftheleftventriclein dynamic2D-echo4-chamberlong-axisimagesoverthecompletecardiaccycle.The proposedalgorithmisbasedonclassicimageprocessingtechniques,includingtime- averagingandwavelet-baseddenoising,edgeenhancementfiltering,morphological operations,homotopymodification,andwatershedsegmentation.Theproposed methodissemi-automatic,requiringasingleuserinterventionforidentificationof thepositionofthemitralvalveinthefirsttemporalframeofthevideosequence. Imagesegmentationisperformedonasetofdynamic2D-echoimagescollected fromanexaminationcoveringtwoconsecutivecardiaccycles. Results:Theproposedmethodisdemonstratedandevaluatedontwelvehealthy volunteers.Theresultsarequantitativelyevaluatedusingfourdifferentmetrics,ina comparisonwithcontoursmanuallysegmentedbyaspecialist,andwithfour alternativemethodsfromtheliterature.Themethod’sintra-andinter-operator variabilitiesarealsoevaluated. Conclusions:Theproposedmethodallowstheautomaticconstructionofthearea variationcurveoftheleftventriclecorrespondingt

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