Semi-automatic algorithm for construction of the left ventricular area variation curve over a complete cardiac cycle 英文参考文献.docVIP
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Meloetal.BioMedicalEngineeringOnLine2010,9:5
/content/9/1/5
RESEARCH
OpenAccess
Semi-automaticalgorithmforconstructionofthe
leftventricularareavariationcurveovera
completecardiaccycle
SalvadorAMeloJúnior1,BrunoMacchiavello2*,MarcelinoMAndrade3,Jo?oLACarvalho1,3,HervaldoSCarvalho1,4,
DanielFVasconcelos4,PedroABerger2,AdsonFdaRocha1,FranciscoAONascimento1
*Correspondence:
bruno@image.unb.br
2DepartmentofComputerScience,
UniversityofBrasília,Brasília,DF,
Brazil
Abstract
Background:Two-dimensionalechocardiography(2D-echo)allowstheevaluationof
cardiacstructuresandtheirmovements.Awiderangeofclinicaldiagnosesarebased
ontheperformanceoftheleftventricle.Theevaluationofmyocardialfunctionis
typicallyperformedbymanualsegmentationoftheventricularcavityinaseriesof
dynamicimages.Thisprocessislaboriousandoperatordependent.Theautomatic
segmentationoftheleftventriclein4-chamberlong-axisimagesduringdiastoleis
troublesome,becauseoftheopeningofthemitralvalve.
Methods:Thisworkpresentsamethodforsegmentationoftheleftventriclein
dynamic2D-echo4-chamberlong-axisimagesoverthecompletecardiaccycle.The
proposedalgorithmisbasedonclassicimageprocessingtechniques,includingtime-
averagingandwavelet-baseddenoising,edgeenhancementfiltering,morphological
operations,homotopymodification,andwatershedsegmentation.Theproposed
methodissemi-automatic,requiringasingleuserinterventionforidentificationof
thepositionofthemitralvalveinthefirsttemporalframeofthevideosequence.
Imagesegmentationisperformedonasetofdynamic2D-echoimagescollected
fromanexaminationcoveringtwoconsecutivecardiaccycles.
Results:Theproposedmethodisdemonstratedandevaluatedontwelvehealthy
volunteers.Theresultsarequantitativelyevaluatedusingfourdifferentmetrics,ina
comparisonwithcontoursmanuallysegmentedbyaspecialist,andwithfour
alternativemethodsfromtheliterature.Themethod’sintra-andinter-operator
variabilitiesarealsoevaluated.
Conclusions:Theproposedmethodallowstheautomaticconstructionofthearea
variationcurveoftheleftventriclecorrespondingt
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